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比伐卢定在经皮冠脉介入治疗术中的应用 被引量:3

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摘要 目的探讨比伐卢定在经皮冠脉介入治疗术中的临床应用价值。方法择期行经皮冠脉介入治疗术的患者40例,将其随机分为对照组和观察组,每组20例。对照组患者在给予普通肝素进行抗凝治疗,观察组患者给予比伐卢定进行抗凝治疗,对两组患者用药前后不同时间点的血小板最大聚集率进行比较,同时对比其手术成功率和术后1个月内心血管不良事件、出血情况的发生率。结果两组患者在用药后10 min、用药结束后,血小板最大聚集率的比较,差异有统计学意义(P<0.05)。两组患者手术均成功,且术后30 d内均未出现心血管不良事件。观察组和对照组轻度出血的发生率分别为5.0%和15.0%,差异有统计学意义(P<0.05)。结论在实施经皮冠脉介入治疗术的过程中,使用比伐卢定进行抗凝治疗,不仅能获得良好的临床疗效,还可以在术中抑制血小板活性,降低术后出血事件的发生率,安全有效,值得临床推广应用。
作者 张奇峰
出处 《中国现代药物应用》 2015年第7期108-110,共3页 Chinese Journal of Modern Drug Application
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