近乳晕区早期乳腺癌整形保乳术30例临床研究

Clinical study of oncoplastic breast-conserving surgery for the treatment of 30 cases of early breast cancer

目的:评价近乳晕区早期乳腺癌患者行整形保乳术的临床效果。方法:将2011年2月至2013年11月唐山市人民医院乳腺外科(二)接受保乳手术治疗的60例近乳晕区早期乳腺癌患者随机分成两组,试验组30例行整形保乳术,对照组30例行标准保乳术,比较两组术中切除的乳腺局部标本质量,肿瘤距外科切缘最近的距离,术后患乳美容效果。结果:试验组与对照组患者术中切除的乳腺标本量为(71.03±12.92)g vs.(41.53±7.13)g,肿瘤距外科切缘最近的距离为(13.30±2.97)mm vs.(10.63±1.65)mm,比较两组差异具有统计学意义(P<0.05);试验组与对照组术后患者满意率为93.33%vs.83.33%,差异无统计学意义(P>0.05)。结论:试验组切除的乳腺组织量更大、范围更广,而术后患乳美容效果与对照组无差别。早期乳腺癌患者实施整形保乳术可行、有效。

Objective：To evaluate the clinical effects of oncoplastic breast-conserving surgery on patients with early breast can-cer near the mammary areola. Methods：A total of 60 patients with early breast cancer underwent breast-conserving surgery in the Sec-ond Department of Breast Surgery, Tangshan People＇s Hospital from February 2011 to November 2013. These patients were random-ized into two groups, namely, the experimental Group A （n=30） and the control Group B （n=30）. Oncoplastic breast-conserving surgery was performed on the patients in Group A, whereas Group B underwent standard breast-conserving surgery. The specimen weight of the locally excised breast, the nearest distance of the tumor to the surgical margins, and the postoperative cosmetic result of the affected breast were compared between the two groups. Results： The specimen weights of the locally excised breast were 71.03 ± 12.92 and 41.53±7.13 g, and the nearest distances of the tumor to the surgical margins were 13.30±2.97 and 10.63±1.65 mm in Groups A and B, respectively, with significant differences between the two groups （P0.05）. Con-clusion：A larger amount of excised breast tissue and a wider scope of surgical margins were observed in Group A patients. However, the postoperative cosmetic result of the affected breast was almost similar for both groups. Therefore, oncoplastic breast-conserving sur-gery is a feasible and effective approach for early breast cancer patients.