期刊文献+

基于动态脚本语言的食管癌IMRT计划设计

IMRT design for esophageal carcinoma based on dynamic scripts
下载PDF
导出
摘要 目的利用Solaris 10操作系统中自带的Perl程序创建具有自适应性质的动态脚本,实现调强放射治疗(IMRT)计划设计的自动执行,并研究其在计划设计中的应用前景。方法选取6例食管癌患者,利用Perl程序创建动态脚本,通过脚本回放,实现IMRT放疗计划的设计,并利用体积剂量,计划完成时间等参数与人工设计的计划进行对比。结果在不明显改变计划质量的前提下,脚本计划时间(12.70±1.47)min相比人工计划时间(27.72±2.29)min平均缩短15 min,差异有统计学意义(P<0.05)。结论利用Perl程序创建动态脚本能够自适应靶区与剂量,通过脚本回放可快速完成IMRT计划的设计。 Objective Underwent adaptive dynamic scripts based on the Perl program of Solaris 10 operating sys-tem and scripting playback of pinnacle system which automatically performed the plan of intensity modulated radio-therapy and analyzed the dose distribution produced by the dynamic scripts, and then explored them in the treat-ment plan of intensity modulated radiotherapy. Methods Six patients with esophageal carcinoma received radiother-apy were selected. Two IMRT plans for each patient were designed: the artificial plan and the plan based on the dynamic scripts through playback function. The dose volume histogram, plan completion time, and other parame-ters were compared respectively. Results The average time of IMRT plan(12. 70 ± 1. 47) minutes achieved by the application of dynamic scripts was 15 minutes shorter than that of the artificial plan(27. 72 ± 2. 29) minutes, and the difference was statistically significant ( P〈0. 05 ) . Conclusion The dynamic scripts based on the Perl program can adapt the targets and dose, and can quickly fulfill the IMRT plan through playback function.
出处 《安徽医科大学学报》 CAS 北大核心 2015年第2期209-213,共5页 Acta Universitatis Medicinalis Anhui
基金 安徽省高校省级自然科学研究项目(编号:KJ2010B380)
关键词 PERL IMRT 脚本 食管癌 Perl IMRT script esophageal carcinoma
  • 相关文献

参考文献9

  • 1Pinnacle3 Planning reference guide [ M]. 9201-5136A-ENG Rev A. Fitchburg USA. Philips Medical System. 2008.
  • 2S Geoghegan. Scripting on the Pinnacle3 Treatment Planning Sys- tem[ M]. Royal Perch Hospital, 2007.
  • 3柏朋刚.基于数据驱动的鼻咽癌调强计划自动化设计[J].医疗装备,2013,26(2):6-9. 被引量:7
  • 4陈维军,狄小云,王彬冰,白雪,祝成龙.Pinnacle计划系统脚本在调强放疗计划中的应用研究[J].中国医学物理学杂志,2010,27(3):1858-1861. 被引量:13
  • 5Holdsworth C, Hummel-Kramer S M, Phillips M. Scripting in ra- diation therapy: an automatic 3D beam-naming system[ J]. Med Dosim, 2011, 36(3): 272-5.
  • 6Yang D, Moore K L. Automated radiotherapy treatment plan integ- rity verification[J]. Med Phys, 2012, 39(3) : 1542 -51.
  • 7Yaddanapudi S, Yang D, Moore K, et al. SU-GG-T-202: Auto- mation of patient specific IMRT QA plan generation [ J ]. Med Phys, 2010, 37(6) : 3231.
  • 8Wu B, Pang D, Simari P, et al. Using overlap volume histogram and IMRT plan data to guide and automate VMAT planning: A head-and-neck ease study [ J ]. Med Phys, 2013, 40 ( 2 ) : 021714.
  • 9王彬冰,狄小云,陈维军,侯氢.基于遗传算法的三维适形放疗射野入射角度最优化研究[J].中华放射肿瘤学杂志,2008,17(4):304-307. 被引量:4

二级参考文献29

  • 1金大伟,戴建荣,李晔雄,余子豪.前列腺癌调强放疗的治疗方案比较[J].中华放射肿瘤学杂志,2005,14(1):47-51. 被引量:43
  • 2陈超敏,唐木涛,周凌宏,吕庆文,王卓宇,陈光杰.调强放射治疗中剂量计算与射野参数优化研究[J].中华放射医学与防护杂志,2006,26(3):248-250. 被引量:6
  • 3Chen Y,Michalski D,Houser C,et al. Galvin JM, A deterministic iterative least-squares algorithm for beam weight optimization in conformal radiotherapy. Phys Med Biol,2002,47 : 1647-1658.
  • 4Hou Q, Wang J, Chen Y, et al. Beam orientation optimization for IMRT by a hybrid method of the genetic algorithm and the simulated dynamics. Med Phys ,2003 ,30 :2360-2366.
  • 5Borffeld J,Schlegel W. Optimization of beam orientation in radiation therapy: some theoretical considerations. Phys Med Biol, 1995,58:291-504.
  • 6Soderstrom S, Brahme A. Which is the most suitable number of photon beams in coplanar radiation therapy? Int J Radiat Oncol Biol Phys, 1995,33 : 151-159.
  • 7Cho BC,Roa WH, Robinson D,et al. The development of targeteye-view maps for selection of coplanar or noncoplanar beams in conformal radiotherapy treatment planning. Med Phys, 1999,26 : 2367-2372.
  • 8Rowbottom CG,Webb S,Oldham M. Improvements in prostate radiotherapy from the customization of beam directions. Med Phys, 1998,25 : 1171-1179.
  • 9Schreibmann E, Lahanas M, Uricchio R,et al. A geometry based optimization algorithm for conformal external beam radiotherapy. Phys Med Biol, 2003,48:1825-1841.
  • 10Schreibmann E, Xing L. Dose-volumed based ranking of incident beam direction and its utility in facilitating IMRT beam placement. Int J Radiat Oncol Biol Phys ,2005 ,6 :584-593.

共引文献20

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部