尿碘含量与甲状腺结节患病率的关系

Relationship of thyroid nodular diseases and urine iodine

目的探讨尿碘含量与甲状腺结节的关系。方法根据彩色多普勒超声检查结果将175例健康体检者分为甲状腺结节组(A组,80例)和无甲状腺结节组(B组,95例),用砷铈催化分光光度法测定两组尿碘含量。结果尿碘浓度<100μg/L和>200μg/L者甲状腺结节患病率大于尿碘100-200μg/L者(65.79%和56.86%vs.30.23%)(P<0.01)。结论碘摄入量和甲状腺结节呈现U字型曲线的关系,甲状腺结节与高尿碘及低尿碘均有关。

Objective To study the relationship of thyroid nodular diseases and urine iodine. Methods On the basis of color Doppler ultrasound examination for the thyroids, 175 healthy people were assigned into two groups of A（with thyroid nodules, 80 cases） and B（without thyroid nodules, 95 cases）. The urine iodine concentration was detected by As （ Ⅱ ）-Ce4＋ catalytic spectrophotometry. Results The prevalence of thyroid nodules was higher in the people with the urinary iodine concentrations of 〈 100 μg/L and 〉 200μg/L than those with an urinary iodine concentration of 100-200μg/L（65.79% and 56.86% vs. 30. 23%） （P〈0. 01）. Conclusion Iodine intake and thyroid nodules present a U-shaped curve relationship. Both of high and low urinary iodine all are related to the prevalence of thyroid nodules.