造血微环境对造血干细胞的代谢调控机制及其在造血系统疾病中的作用

Metabolic regulation of bone marrow microenvironment on hematopoietic stem cells and its role in hematologic diseases

导出

摘要造血干细胞（HSC）是机体骨髓中一群具有自我更新和多向分化潜能的细胞.其数量（即HSC池的大小）和功能的稳态（homeostasis）对维持机体正常健康的造血系统和生理功能必不可少;因此调节HSC的功能对保持机体在生命周期中有效造血至关重要.

作者姚利阮长耿陈子兴

机构地区苏州大学附属第一医院、江苏省血液研究所

出处《中华血液学杂志》 CAS CSCD 北大核心 2015年第2期168-171,共4页 Chinese Journal of Hematology

基金科技部重大科研计划“973”计划子课题（2011CB933501）国家自然科学基金面上课题（81070402）江苏省高校优势学科建设工程项目

关键词造血系统疾病造血干细胞造血微环境代谢调控多向分化潜能生理功能自我更新生命周期

参考文献40

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中华血液学杂志

2015年第2期

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