光固化快速成型双管道镁合金/生物陶瓷复合增强骨支架的力学性能研究

Research on the Mechanical Properties of Bone Scaffold Reinforced by Magnesium Alloy/Bioceramics Composite with Stereolithography Double Channels

针对多孔生物陶瓷骨支架力学强度差的问题,结合生物可降解镁合金良好的力学性能,提出了一种制备双管道镁合金/生物陶瓷复合增强骨支架的方法。首先设计具有互不连通双管道的支架结构,然后利用光固化快速成型结合凝胶注模法制备具有双管道的生物陶瓷支架,再利用低压铸造法向双管道生物陶瓷支架的次级管道中灌注熔化的AZ31镁合金,镁合金固化后即得到镁合金/生物陶瓷复合骨支架。支架压缩实验测得单管道生物陶瓷支架的压缩强度为(9.76±0.64)MPa,而镁合金/生物陶瓷复合骨支架的压缩强度为(17.25±0.88)MPa。镁合金/生物陶瓷复合骨支架具有明显的力学增强能力。

Focusing on the poor mechanical strength of porous bioceramics bone scaffold,and taking into account of the good mechanical properties of biodegradable magnesium alloy,we proposed a novel method to fabricate magnesium alloy/bioceramics composite bone scaffold with stereolithography double channels.Firstly,a scaffold structure without mutually connected double channels was designed.Then,an optimized bioceramics scaffold was fabricated according to stereolithography and gel-casing.Molten AZ31 magnesium alloy was perfused into the secondary channel of scaffold by low-pressure casting,and magnesium alloy/bioceramics composite bone scaffold was obtained when magnesium alloy was solidified.The compression test showed that the strength of bioceramics scaffold with only one channel and without magnesium alloy was（9.76±0.64）MPa,while the strength of magnesium alloy/bioceramics composite scaffold with double channels was（17.25±0.88）MPa.It can be concluded that the magnesium alloy/bioceramics composite is obviously able to improve the scaffold strength.