三维经胆道超声造影对肝门部胆管癌的诊断价值的初步研究

Preliminary Study of Value of Three-dimensional Intra-biliary Contrast Enhanced Ultrasound in Diagnosis of Hilar Cholangiocarcinoma

【目的】探讨三维经胆道超声造影对于肝门部胆管癌的诊断价值。【方法】回顾分析16例确诊为肝门部胆管癌患者,比较常规超声和三维经胆道超声造影对于肝门部胆管癌分型的诊断符合率,以及对左右肝内胆管间的梗阻程度的诊断符合率,以X线胆道造影作为诊断金标准。【结果】三维经胆道超声造影对肝门部胆管癌的分型诊断符合率为93.8%(15/16),常规超声为43.8%(7/16),三维经胆道超声造影优于常规超声(P=0.037);三维经胆道超声造影对于左右肝管间梗阻程度诊断符合率为93.8%(15/16),常规超声的诊断符合率为68.8%(11/16),两者比较无统计学差异(P=0.172)。【结论】三维经胆道超声造影可以提高超声对肝门部胆管癌的分型诊断符合率,同时判断左右肝内胆管间的梗阻程度。

【Objective】To explore the value of three-dimensional intra-biliary contrast-enhanced ultrasound（3D-IB-CEUS） in the diagnosis of hilar cholangiocarcinoma.【Methods】 Sixteen patients who were confirmed to be hilar cholangiocarcinomas were enrolled in this study.The accuracies of classification and biliary obstructive degree were compared between conventional ultrasound and 3DIB-CEUS.X-ray cholangiography was taken as golden standard.【Result】 The accuracies of classification were 93.8%（15/16） in 3DIB-CEUS and 43.8%（7/16） in conventional ultrasound.The accuracy of 3D-IB-CEUS was superior to conventional ultrasound（P =0.037）.The accuracies of biliary obstructive degree were 93.8%（15/16） in 3D-IB-CEUS and 68.8%（11/16） in conventional ultrasound.There were no significant differences between that of 3D-IB-CEUS（P=0.172） and conventional ultrasound.【Conclusion】Compared with conventional ultrasound,3D-IB-CEUS could improve the accuracies of classification in hilar cholangiocarcinoma.3DIB-CEUS was also useful in the diagnosis of the biliary obstructive degree.