系统性红斑狼疮中医病因病机及辨证分型的研究进展

Research Progress on Etiology,Pathogenesis and Syndrome Differentiation of Systemic Lupus Erythematosus in Traditional Chinese Medicine

系统性红斑狼疮(SLE)是一种病因不明、累及多系统、多器官的自身免疫性疾病;病变除皮肤关节损害外,常累及内脏,尤以肾、心、肝损害为多见,危及患者生命和生活质量。究其病因病机,先天禀赋不足、肝肾亏虚是SLE发病的主要原因。该病属本虚标实之证,火热亢盛为标,肝肾阴亏为本,辨证当需分清标本虚实。该文对SLE的中医病因病机及辨证分型进行综述。

Systemic lupus erythematosus（ SLE） is an autoimmune disease involving multi-systems and multi-organs with unknown etiology,with damages to joints,skin,internal organs,especially the kidney,heart,and liver,devastating the lives of patients and their life quality. Investigating its etiology and pathogenesis： lack of innate endowment and liver and kidney deficiency are the main reasons for the onset of SLE. The disease belongs to deficient root with excessive superficial,excessive hot as the superficial,yin deficiency in liver and kidney as root. Differentiation of syndromes needs to draw a clear distinction between deficiency and excess. Here is to make a review of the etiology,pathogenesis and syndrome differentiation of SLE in traditional Chinese medicine.