PUL患者应用血清β-hCG水平及子宫内膜厚度检查对妊娠结局的影响分析

Analysis on serum β-hCG level and effect of endometrial thickness examination on pregnancy outcome

目的：探讨检测人血清β-人绒毛膜促性腺激素（β-hCG）及子宫内膜厚度与不明位置妊娠（PUL）妇女妊娠结局的关系。方法：回顾性分析该院妇科门诊及住院部2013年7月-2014年8月就诊及收治的具有“停经、尿妊娠试验阳性”的98例PUL患者的就诊资料,根据妊娠结局分为宫内孕组（37例）、宫外孕组（26例）、自然流产组（35例）,对3组患者的β- CG、子宫内膜厚度值及相关激素水平进行比较分析。结果：早期检测PUL患者的β-hCG、子宫内膜厚度、β-hCG比值、P值、E2值在3组间差异均有统计学意义（P〈0.05）;宫外孕组的β-hCG、子宫内膜厚度、β-hCG比值、P值、E2值均显著低于宫内孕组、自然流产组（P〈0.05）;自然流产组的β-hCG、子宫内膜厚度、β-hCG比值、P值、E2值均显著低于宫内孕组（P〈0.05）。结论：对于PUL妇女早期检查β-hCG、子宫内膜厚度对判定宫外孕及流产有一定的临床价值。

Objective： To explore the relationship between serum beta- human chorionic gonadotropin （β -hCG）, endometrial thickness and pregnancy outcome of women with pregnancy of unknown location （PUL） . Methods： The medical data of 98 patients with PUL （ menopause, urine pregnancy test was positive） treated in outpatient department and inpatient department of the hospital from July 2013 to August 2014 was analyzed retrospectively, all the patients were divided into intrauterine pregnancy group （37 patients）, ectopic pregnancy group （26 patients） and spontaneous abortion group （35 patients） ;β -hCG levels, endometrial thicknesses and related hormones levels in the three groups were compared and analyzed. Results： There were statistically significant differences in β-hCG level, endometrial thickness,β - hCG ratio, progesterone and estradiol levels among the three groups （ P 〈 0. 05 ） ; β- hCG level, endometrial thickness, β- hCG ratio, progesterone and estradiol levels in ectopic pregnancy group were statistically significantly lower than those in intrauterine pregnancy group and spontaneous abortion group （ P 〈 0.05 ） ; β- hCG level, endometrial thickness, β - hCG ratio, progesterone and estradiol levels in spontaneous abortion group were statistically significantly lower than those in intrauterine pregnancy group （ P 〈 0. 05 ） . Conclusion ： Early detection of β - hCG level and endometrial thickness has a certain clinical value in determining ectopic pregnancy and abortion among PUL women.