补肾化痰颗粒治疗血管性痴呆肾精亏虚痰浊蒙窍证

Bushen Huatan granule in the treatment of vascular dementia kidney deficiency and phlegm resistance brain

目的观察补肾化痰颗粒治疗血管性痴呆肾精亏虚痰浊蒙窍证的临床疗效。方法将符合纳入标准的140例患者随机分为治疗组和对照组,各70例,分别给予补肾化痰颗粒和都可喜,连续服用12周,观察临床疗效及其血流变指标、血Hcy水平。结果 2组均能较好的改善患者认知、记忆、日常生活能力、血流变指标及血Hcy水平,且治疗组在认知的改善程度上明显优于对照组(P<0.05)。结论补肾化痰颗粒治疗血管性痴呆(肾精亏虚痰浊蒙窍证)能改善患者血液流变学指标和血Hcy水平,尤其对于认知功能的改善程度明显。

Objective To observe the kidney phlegm granule in the treatment of vascular dcmentia with kidney deficiency and phlegm resistance brain the clinical curative effect. Methods The 140 patients were randomly divided into treatment group and control group（ n = 70）,give Bushen Huatan granule and Duxil respectively,for 12 weeks,observe the clinical effect and its indexes,blood Hcy levels. Results Two groups can better improve the patients＇ cognition,memory,daily life ability,indexes and blood Hcy levels,and improve the degree of cognitive therapy group was obviously better than the control group（ P〈0. 05）. Conclusion Bushen Huatan granule in the treatment of vascular dcmentia with kidney deficiency and phlegm resistance brain curative effect,can improve the indexes of blood rheology and blood Hcy levels,especially improved cognitive function significantly.