中西医结合联合外治对中老年女性复发性尿路感染的疗效影响研究

Effect of Integrated Traditional Chinese and Western Medicine and External Therapy in Treatment of Recurrent Urinary Tract Infection for Elderly Women

目的:探讨中西医结合兼外治对中老年女性复发性尿路感染的影响。方法:以120例中老年女性复发性尿路感染急性期患者为研究对象,随机分为A、B、C 3个组,分别给予西医抗菌治疗、抗菌治疗+口服中药治疗以及抗菌治疗+口服中药+外治,观察3组症状缓解及消失时间、尿常规恢复正常时间,临床疗效以及1年随访期内复发情况。结果:3组症状缓解时间差异没有显著性(P>0.05);症状消失时间组间差异有显著性(P<0.05),B组明显短于A组(P>0.05)。尿常规恢复正常时间3组间差异明显(P<0.05),B组优于A组(P<0.05),C组优于B组(P<0.05)。疗效评价显示,C组较B组治愈率高而无效率低,B组治愈率高于A组,3组间及组间比较差异均有统计学意义(P<0.05或0.01)。3组患者在治疗期间发生不良反应情况相当,差异没有显著性(P>0.05)。从患者治疗开始,随访1年,3组平均复发次数差异明显(P<0.01),C组复发率最低,明显优于B组,而B组优于A组(P<0.01)。结论:对于中老年女性尿路感染,在西医抗菌治疗的基础上配合中药口服,症状消失时间和尿常规恢复正常的时间短,复发率低;在中西药的基础上再配合外洗和艾灸,则可进一步降低复发率,利于提高复发性尿路感染的远期疗效。

Objective：To investigate the effect of combining Chinese and Western medicine and external therapy in treatment of recurrent urinary tract infection for elderly women.Methods：120 cases of elderly women with recurrent urinary tract infection in acute period were divided into A,B and C groups randomly and were administered western medicine antibacterial therapy,antibacterial ＋ oral Chinese medicine treatment and antibacterial ＋ oral Chinese medicine ＋ external therapy respectively.And then,the symptoms remission and disappeared time,urine routine recovered time,clinical efficacy and recurrence rate within 1 year follow-up of three groups were observed.Results：The time of symptoms remission between three groups was not significant（P〉0.05）.The symptoms disappeared time among three groups had significant difference（P〈0.05） and B group＇ s was significantly shorter than that in group A（P〉0.05）.The difference of urine routine recovered time among three groups was significant（P〈0.05） and B group＇s was shorter than that in group A（P〈0.05） and C group＇s was shorter than that in group B（P〈0.05）.The evaluation of clinical effect displayed that C group was better than B group with higher cure rate and low inefficiency and the cure rate of B group was higher than that in group A.The differences among three groups were statistically significant（P〈0.05 or P〈0.01）.The adverse reactions occurred during the treatment in three groups were roughly the same and the difference was not significant（P〉0.05）.The patients were followed up for 1 year from the start of treatment and the difference of the average recurrence times among the three groups had obvious difference（P〈0.01） and the recurrence rate of C group was the lowest,significantly better than that of group B while group B was better than group A as well（P〈0.01）.Conclusion：For the treatment of urinary tract infection in elderly women,combined oral treatment of traditional Chinese medicine on the basis of antibacterial western medicine,the symptoms disappeared time and urine routine recovered time were short and the recurrence rate was low.By combining with external washing or moxibustion on the basis of treatment of Chinese and Western medicine,it could further reduce the recurrence rate of recurrent urinary tract infection and was beneficial to improve the long-dated curative effect.