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白细胞介素33/ST2信号转导通路与冠心病关系的研究进展 被引量:5

Research progress in the relationship between interleukin 33/ST2 pathway and coronary atherosclerotic heart disease
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摘要 ST2是近年来新发现的一个心肌标志物,而白细胞介素33(interleukin 33,IL-33)是ST2的特异配体,通过与ST2结合,IL-33/ST2组成一种新的信号转导通路,参与T细胞介导的免疫应答,在多种炎症、免疫疾病中起着重要的作用。多项研究表明,ST2能够独立预测心力衰竭及心肌梗死患者的死亡率[1-4]。另外,ST2在动脉粥样硬化(atherosclerosis,AS)
出处 《中国心血管杂志》 2015年第1期72-74,共3页 Chinese Journal of Cardiovascular Medicine
基金 国家自然科学基金课题(81172750)~~
关键词 冠心病 白细胞介素33 ST2 Coronary heart disease Interleukin 33 ST2
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