住院卧床患者应用气压治疗仪预防下肢深静脉血栓形成疗效的Meta分析

A Meta analysis of preventing effect of pressure treatment instrument on deep venous thrombosis of lower extremity for hospitalized patients

目的系统评价气压治疗仪对住院卧床患者预防下肢深静脉血栓形成的效果。方法利用计算机检索国内外相关文献，根据NoteExpress软件进行文献筛选和查重，对符合纳入标准的随机对照试验或非随机对照试验文献采用RevMan5．2软件进行数据合并分析。结果共纳入13篇文献，采用固定效应模型分析，纳入研究对象为1194例，实验组599例，对照组595例。文献分析结果显示，气压治疗仪可降低下肢深静脉血栓发生率（OR=0．24，0R95％CI：0．15～0．37，P〈0．01），并提高下肢静脉血流速度（OR=0．52，0R95％CI：0．25～0．80，P〈0．01）。更换统计效应模型进行敏感性分析结果显示，研究结果稳定性高，结论可靠。结论气压治疗仪可以降低住院卧床患者下肢深静脉血栓的发生率，延长其生存时间和提高生活质量，并可减少一些药物预防血栓所产生的并发症，越来越受到临床工作者的青睐，值得进一步推广和应用。

Objective We aimed to assess systematically the effect of pressure treatment instrument on pre-venting deep venous thrombosis of lower extremity for hospitalized patients. Methods Relative literature was searched by computer at home according to the inclusion and the exclusion criteria,which were ana-lyzed by RevManS.2 software and literature selection and repetition were used according to the Note Ex-press software. Results A total of 13 studies of randomized controlled or not randomized con- trolled trials were brought into the study by fixed effects model A total of 1 194 were included into the study, 599 in the experimental group and 595 in the control group. Literature analysis showed that pressure treatment in-strument can decrease the incidence rate of deep venous thrombosis of lower extremity （0R=0.24,0R95% Cl：0.15N0.37,P〈0.01 ） and increase venous blood flow velocity （OR=0.52,0R95%CI：0.25~0.80,P〈0.01）. By replacing the statistical effect model, the sensitivity analysis showed a stable and reliable result con- clusion. Conclusions Pressure treatment device can reduce the incidence rate of lower extremity deep venous thrombosis in hospitalized patients, prolong the survival time and improve the quality of life, and can also reduce the complications caused by anti-thromboembolic drugs. It is favored by clinical workers more and more, and it is worthy of further promotion and application.