天津地区脑梗塞载脂蛋白B基因多态性与危险因素的关系

The Relationship between apo-B Gene Polymorphism Characters of Infarction and the Relative Risk Factors in Tianjin Area

目的探讨天津市脑梗塞的基因型特点及其与危险因素的关系。方法采用 L ogistic回归的分析方法 ,分析不同危险因素与基因型的关系。结果本人高血压病史及高血压、脑卒中家族史与 X+基因型有关。结论危险基因型是通过影响高血压。

Objective To explore the relationship of apo-B genotype characters of infarction to the risk factors in Tianjin area.Method With Logistic regression analysis,the relation between apo-B genotype and the risk factors was studied.Result The single factor analysis found that the X + genotype was related to hypertension,the family history of hypertension and stroke,P<0.05.The multiple regression analysis result indicated that X + genotype related to the family history of stroke of the siblings,P<0.05.Conclusion The X + genotype of the infarction increase the occurrence opportunity of infarction by means of influencing the family disease history of hypertension and stroke.