西黄胶囊联合西药治疗晚期癌症疼痛临床研究

Clinical Research on West Yellow Capsules Combined with Western Medicine in the Treatment of Advanced Cancer Pain

目的:观察西黄胶囊联合西药治疗晚期癌症患者疼痛的临床疗效。方法:将46例晚期癌症患者随机分为治疗组(n=24)与对照组(n=22)。治疗组患者口服西黄胶囊和盐酸吗啡缓释片(美菲康)治疗,对照组患者口服美非康治疗;治疗2周后评价疗效,观察比较两组患者的止痛疗效、卡氏评分、不良反应等指标。结果:治疗组疼痛症状明显改善,生活质量明显提高,临床疗效、KPS评分治疗组均优于对照组(P均<0.05),差异具有统计学意义。结论:西黄胶囊联合吗啡缓释片治疗晚期癌症疼痛疗效显著,值得临床推广应用。

Objective：To study the effect of Xihuang capsules and morphine hydrochloride sustained-release tablets in the treatment of the late-term and advanced cancerous pain. Methods： 46 cases of lat-term and advanced cancer patients were randomly divided in- to treatment group and control group. The treatment group received morphine hydrochloride sustained release tablets and Xihuang capsules;the control group received morphine hydrochloride sustained release tablets. After two weeks,observed the improvement of pain and quality of life. Results ： The pain and quality of life of the treatment group significant improved. Conclusion： Xihuang cap- sules and morphine hydrochloride sustained-release tablets can significantly improve the symptoms,and improve the quality of life in the treatment of cancerous pain.