小剂量盐酸苯海索辅助治疗缺血性脑血管病假性延髓麻痹患者吞咽障碍临床分析

Analysis of treatment of pseudobulbar paralysis reulted by stroke with a small dose of trihexyphenidyl hydrochloride

目的探讨小剂量苯海索辅助治疗缺血性脑血管病假性延髓麻痹患者吞咽障碍的临床疗效,以提高患者生活质量。方法对本科2005年至2012年收治的186例脑血管病假性延髓麻痹患者分为治疗组96例和对照组90例,遵照按脑卒中指南常规用药,治疗组在对照组治疗的基础上加用小剂量苯海索辅助治疗,治疗前后对患者进行标准吞咽功能评估(SSA)和洼田氏饮水试验评定。结果治疗组患者应用小剂量苯海索辅助治疗后有明显疗效,与对照组疗效差异有统计学意义(p<0.05)。结论小剂量苯海索辅助治疗能够更大程度的提高患者的吞咽功能,能改善患者的进食状况,提高患者的生活质量。

Objective Analysis the clinical effect of a small dose of trihexyphenidyl hydrochloride adjuvant therapy after stroke patients with dyphagia of pseudobulbar paralysis, the purpose is in order to improve the quality of life of patients. Methods 186 cases of cerebral vascular encephalopathy of pseudobulbar paralysis patients in my department from 2005 to 2012 were divided into treatment group 96 and control group 90 cases, control group received conventional therapy of stroke guide , the treatment group treated with small dose of trihexyphenidyl hydrochloride adjuvant therapy before and after treatment in patients with swallowing function standard assessment （SSA） and depression cropland water drinking test and evaluation. Results The patients in the treatment group the application of small dose of trihexyphenidyl after adjuvant therapy had obvious curative effect, and control groups was statistically significant （p〈0.05）. Conclusion A small dose of trihexyphenidyl hydrochloride adjuvant therapy to a greater degree of improvement in patients with swallowing function and can improve the patient＇s eating status, improve the patients＂ life level.