原发性眼睑痉挛100例临床分析

Clinical analysis of primary blepharospasm: A report of 100 cases

目的分析原发性眼睑痉挛患者临床特点及治疗情况,提高临床医师对该病的临床诊治率。方法回顾性分析我院收治的100例原发性眼睑痉挛患者的一般资料、早期表现、诊断及治疗情况。结果 100例原发性眼睑痉挛患者的发病年龄为（56.4±2.7）岁,确诊时病程为2~120个月,平均30个月。100例患者中眼干涩是最常见的早期非痉挛症状（54例）,其后依次是眼睑睁开费力（39例）、眨眼次数增多（32例）、畏光（32例）。100例患者中仅10例初次就诊时被正确诊断,有90例早期诊断为其他疾病,包括干眼症、结膜/角膜炎、重症肌无力、神经症等。结论原发性眼睑痉挛的早期临床表现多样,早期识别率低,大多数病例未得到及时正确的治疗,眼科医师应提高对该病的认识。

Ohjeetive To analyze the clinical characteristics and treatment of primary blepharospasm, and improve the rate of diagnosis and treatment. Methods A retrospective analysis of clinical date of 100 blepharospasm patients in our hospital was performed, including general information, early manifestations, diagnosis and treat- ments. Results The age at onset of the 100 patients was （56.4 _＋ 2.7） years,the dura- tion was from 2 months to 120 months,averaged 30 months. Dry eye was the most com- mon of early non-spasm symptoms （54 cases）, followed by eyelid open laborious （39 cases） ,increased blink frequency （ 32 cases）, photophobia （ 32 cases）. In the 100 cases, while only l0 cases were correctly diagnosed at the initial visit,90 cases were early diag- nosed for other diseases, such as dry eye, conjunctival / keratitis, myasthenia gravis, mental disorders, etc. Conclusion Early clinical manifestations of blepharospasm di- verse, early recognition is low ,the majority of cases have not gotten timely and correct treatment, and the clinical physician should pay attention to this disease.