有晶状体眼后房型人工晶状体植入术后早期前房形态观察

Observation of of anterior chamber after implantable collamer lens implantation in early stage

目的观察有晶状体眼后房型人工晶状体(implantable collamer lens,ICL)植入术后早期前房形态。方法随机选取接受ICL植入术的近视患者26例(49眼),测量患者术前、术后1个月和3个月的中央前房深度、周边前房深度、前房角、前房容积和眼压,对测量结果进行统计学分析。结果术后1个月,中央前房深度为(3.04±0.21)mm,与术前(3.19±0.27)mm相比,差异有显著统计学意义(P=0.00);2 mm、4 mm和6 mm瞳孔直径区域各方位周边前房深度较术前均有显著下降;0°、180°水平方位术后1个月前房角分别为(27.86±5.46)°和(27.95±5.36)°,较术前(42.05±6.73)°、(41.97±5.65)°显著降低,术后1个月前房容积(129.17±18.90)mm3较术前(214.57±27.41)mm3显著减小,以上各指标在术后1个月和3个月测量值相比差异均无统计学意义(均为P>0.05)。术后1个月眼压为(15.31±2.44)mm Hg(1 k Pa=7.5 mm Hg),较术前(17.46±1.79)mm Hg显著降低(t=6.70,P=0.00),术后3个月恢复至(15.79±2.16)mm Hg,与术后1个月相比差异无统计学意义(t=0.49,P=0.77)。结论 ICL植入术后早期前房形态发生改变,前房深度变浅、前房角变窄,但随访期内各观测指标稳定,未见进行性前房变浅、房角关闭或眼压升高。

Objective To observe the anterior chamber after implantation of im- plantable coUamer lens in early stage. Methods Forty-nine eyes of 26 patients with myopia who accepted ICL implantation were enrolled randomly in this study. Central an- terior chamber depth （CACD） ,peripheral anterior chamber depth （PACD）iridocorneal angle,anterior chamber volume （ACV）and intraocular pressure （IOP）were measured pre-operation, 1 month and 3 months after surgery. Measurements were analyzed with paired-t test. Results The pre-operation and postoperative 1 month CACD were （3.19 ±0.27） mm and （ 3.04 ±0.21 ） mm, respectively, there was statistical difference （P = 0.00） ;PACD of 2 ram,4 mm and 6 mm diameter range decreased statistically com- pared with those before surgery;0° and 180°azimuth iridocorneal angles at postopera- tive 1 month were （27.86 ± 5.46 ） ° and （ 27.95 ± 5.36 ） °, which were significant lower than pre-operation （42.05 ± 6.73 ） ° and （41.97 ± 5.65 ） ° ; The pre-operation and postop- erative 1 month ACV were （214.57 ±27.41 ）mm3 and （129. 17 ± 18.90）mm3. And there was no statistical difference between measurements of 1 month and 3 months after sur- gery （ all P 〉 0.05）. IOP measured at postoperative 1 month was （ 15.31 ± 2.44） mmHg （ 1 kPa = 7.5 mmHg）, which was lower than pre-operation （ 17.46 ± 1.79 ） mmHg （ t = 6. 70 ,P = 0.00）, and IOP returned to （15.79 ± 2.16 ）mmHg at postoperative 3 months, there was no statistical difference compared with postoperative 1 month （ t = 0.49,P = 0.77）. Conclusion In the early period after implantation of implantable collamer lens, the anterior chamber morphology changes significantly, but these indexes are sta- ble, no increasing of IOP, decreasing of ACD and closure of iridocorneal angle was ob- served in the follow-up period.