1Caldwell S,Park SH.The epidemiology of hepatocellular cancer:from the perspectives of public health problem to tumor biology[J].J Gastroenterol,2009,44:96-101.
3Xu W,Chang H,Qin CK,et al.Impact of cotrans-fection with livin and survivin sh RNA expression vectors on bio-logical behavior of Hep G2 Cells[J].Asian Pacific J Cancer Pre-vention,2013,14:5467-5472.
4Wang R,Lin F,Wang X,et al.Silencing Livin gene expression to inhibit proliferation and enhance chemosensitivity in tumor cells[J].Cancer Gene Therapy,2008,15:402-412.
5Liu H,Wang S,Sun H,et al.Inhibition of tumorigenesis and invasion of hepatocellular carcinoma by si RNA-mediated silencing of the livin gene[J].Mol Med Rep,2010,3:903-907.
6Wang Z,Rao DD,Senzer N,et al.RNA interference and cancer therapy[J].Pharm Res,2011,12:2983-2995.
7Kasof GM,Gomes BC.“Livin,a novel inhibitor of apoptosis protein family member,”he[J].J Biol Chemistry,2001,276:3238-3246.
8Augello C,Caruso L,Maggioni M,et al.Inhibitors of apoptosis proteins(IAPs)expression and their prognostic significance in hepatocellular carcinoma[J].BMC Cancer,2009,9:125.
9Wang R,Lin F,Wang X,et al.Silencing livin gene expression to inhibit proliferation and enhance chemosensitivity in tumor cells[J].Cancer Gene Ther,2008,15:402-412.
10Choi J,Hwang YK,Sung KW,et al.Expression of Livin,an antiapoptotic protein,is an independent favorable prognostic factor in child acute lymphoblastic leukemia[J].Blood,2007,109(2):471-477.
4Lin J H,Deng G,HuangQ ,et al.A novel member of the inhibitor apoptosis protein family[J]. Biochem Biophys Res Commun, 2000,279( 3 ) : 820-831.
5Vucic D,Stennicke H R, Pisabarro,et al. ML-IAP,a novel inhibitor of apoptosis that is preferentially expressed in human melanomas[J]. Curr-Biol, 2000, 10( 21 ): 1359-1366.
6Kasnf, Gomes. Livin,a novel inhibitor of apoplosis protein family member[J]. J-Biol-Chem, 2001,276( 5 ) : 3238-3246.
7Sanna M G,da Silva Correia J,Ducrey O,et al. IAP suppression of apoptosis involves distinct mechanisms: the TAKI/JNK1 signaling cascade and caspase inhibition[J]. Mol Cell Biol, 2002,22( 6 ) : 1754-1766.
8Ambrosini G,Adida C,Altieri D C. A novel ant-apoptis gene,survivin,expressed in cancer and Iymphoma[J]. New Med, 1997,3(8) :917-921.
9Hauser H P,Bardrof M,Pyrowolakis G,et al. A giant ubiqitin conjugating enzyme related to lAP apoptosis inhibitor[J].J Cell Biol, 1998,141 ( 6 ) : 1415-1422.
10Li F,Ambrosini G,Chu E Y,et al.Control of apoptosis and mitolic spindle checkpoint by survivin[J]. Nature, 1998,396( 6711 ) : 580-588.