摘要
真菌毒素是产毒真菌产生的次生代谢产物,以木霉、曲霉、毛霉、青霉和根霉为主的丝状真菌是农产品中常见的产毒真菌。阐明农产品中产毒致病微生物的基因组序列信息是揭示真菌特殊遗传性状的基础。截至2013年12月,共有子囊菌门中204个种和担子菌门中62个种的基因组序列已经测序或公布,它们的基因组大小大部分在30-40 Mb。整理了部分已完成基因组测序的具有产毒能力或致病力的真菌基因组信息,并对真菌测序方案、主要产毒真菌及其比较基因组学的研究进展进行了综述。
Mycotoxins, a group of toxins structurally related to secondary metabolites are produced by some fungal strains. It is mainly produced by filamentous fungi, including Trichoderma, Aspergillus, Chaetomium, Penicillium and Rhizopus, existed in agricultural products. Illustrating the genome sequence information of the pathogenic microorganisms in agricultural products, is essential to reveal fungal specific genetic traits. Until to December 2013, a total of 204 species in Ascomycetes and 62 species in Basidiomycete genomic information had been sequenced or published, genomes size from approximately 30 Mb to 40 Mb. This review here provides an overview of available genomic information of toxin-producing fungal or virulent fungus, summarizes the recent development in genome sequencing strategies and main fungal produced mycotoxin, and proposes the future direction of the comparative genomics research on fungi.
出处
《生物技术通报》
CAS
CSCD
北大核心
2015年第2期26-34,共9页
Biotechnology Bulletin
基金
国家"973"计划项目(2013CB127805)
国家公益性行业(农业)科研专项(201203037)
科技基础性工作专项(2013FY113400)
关键词
真菌
真菌毒素
农产品
基因组
比较基因组学
fungi
mycotoxin
agricultural products
genome
comparative genomics
