舒芬太尼复合丙泊酚麻醉在妇科腹腔镜手术中的临床效果观察

To Observe the Clinical Effect of Sufentanil Combined with Propofol Anesthesiain Gynecological Laparoscopic Operation

目的探讨舒芬太尼复合丙泊酚麻醉在妇科腹腔镜手术中的临床效果。方法选取符合要求的病例126例,随机分为舒芬太尼复合丙泊酚组(S组)和芬太尼复合丙泊酚组(F组),观察两组患者手术前后不同时间点的呼吸系统中平均动脉压(MAP)、心率(HR)、脉搏血氧饱和度(SPO2)和脑电双频指数(BIS)变化情况。结果麻醉用药后,两组各项指标均有所下降,T2时S组MAP、HR和BIS明显低于F组(P<0.05),其他时间点无显著性差异,两组患者的SPO2无明显差异;同时,S组睁眼时间和拔管时间明显早于F组,首次诉求疼痛时间晚于F组,均具有极显著性差异(P<0.01);而S组丙泊酚使用量和单位标准化剂量明显低于F组(P<0.05)。结论舒芬太尼复合丙泊酚应用于妇科腹腔镜手术,呼吸系统及血液动力学平稳可控,能有效监测、控制麻醉深度及减少丙泊酚用量,同时舒芬太尼还具有比芬太尼更快速有效及更持久的作用。

OBJECTIVE To investigate the clinical effect of sufentanil combined with propofol anesthesia in gynecological laparoscopic operation. METHODS To meet the requirements of the cases 126 cases, randomly divided into sufentanilcombined with propofol group（group S） and fentanyl combined with propofol group（group F） were observed before and after the operation, mean arterialrespira- tory system at different time points in the pressure（MAP） and heart rate（HR）, pulse oxygen saturation（SPO2） and bispectral index（the changes of BIS）. RESULTS anesthesia after treatment, two groups of indicators weredecreased, T2 MAP, HR and BIS in S group was lower than that in F group（P〈0.05）, no significant differences in other time point, no significant difference between the two groups of patients with SPO2; at the same time, S groupopening time and extubation time was significantly earlier than the F group the first appeal, pain time later than the F group, there were very significant difference（P〈0.01）; and group S propofol of quanti- ties and units withstandard dose was significantly lower than that in F group（P〈O.05）. CONCLUSION Sufentanil combined with propo- fol in gynecologic laparoscopicsurgery, respiratory and hemodynamic stability, can effectively monitor and control the depth of anes- thesia and reduce the dosage of propofol andfentanyl, sufentanil compared with a more rapid and effective role and more lasting for.