归脾汤加减联合黛力新治疗脑卒中后抑郁疗效的临床观察

Clinic Observation on Using Guipi Decoction Combined with Deanxit to Treat Stroke Depression after Stroke

目的研究归脾汤加减联合黛力新治疗脑卒中后抑郁(PSD)的临床疗效。方法依据中国精神疾病分类方案与诊断标准第三版修订本(CCMD-3)中抑郁症的诊断标准诊断、《中医内科学》教材郁症诊断标准,符合肝肾亏损、脾肾两虚病机以及美国国立卫生院神经功能缺损评分(NIHSS)。将60例PSD患者随机分治疗组和对照组,每组各30例,对照组单用黛力新治疗PSD患者,治疗组服用归脾汤加减联合黛力新治疗PSD患者。结果 2组患者治疗前NIHSS评分比较无统计学意义。治疗后两组总有效率比较、NIHSS评分比较差异均有统计学意义(P﹤0.01)。结论归脾汤联合黛力新能明显改善PSD患者抑郁程度,促进神经功能恢复,生活能力恢复,值得临床推广应用。

OBJECTIVE To study the Guipi Decoction combined with Deanxit in treatment of post-stroke depression （PSD） and the clin- ical curative effect. METHODS Based on the Chinese classification and diagnostic criteria of mental disorders Third Edition Revised Edition （CCMD-3） criteria for the diagnosis of depression, in the seventh edition of the higher education of traditional Chinese medi- cine ＂Chinese Medicine Department of internal medicine＂ textbook depression diagnosis standard, with scores of deficiency of liver and kidney, liver and kidney two empty pathogenesis and neural function defect USA National Institutes of Health （NIHSS）. 60 cases of PSD patients were randomly divided into treatment group and control group with 30 cases in each group; the control group： the treatment of patients with PSD with deanxit; treatment group： Guipi Decoction Combined with Deanxit in the treatment of patients with PSD; RESULTS the 2 groups of patients before treatment NIHSS score showed no statistical significance. The two groups after treatment the total efficiency comparison of NIASS score comparison, the differences were statistically significant （P〈O.01）. CONCLU- SION Guipi Decoction Combined with Deanxit could significantly improve the degree of depression in patients with PSD, and promote the recovery of nerve function disorder, life ability recovery, worthy of clinical application.