保肾巴布剂穴位贴敷对慢性肾脏病患者生存质量的影响

Effect of Acupoint Application with Baoshen Cataplasm on the Quality of Life in Patients with Chronic Kidney Diseases

目的观察保肾巴布剂穴位贴敷法治疗慢性肾脏病(CKD)患者的临床疗效及其对患者生存质量的影响。方法将60例CKD患者随机分为A组和B组,每组30例,B组予西医常规治疗,A组在西医常规治疗的基础上,予保肾巴布剂穴位贴敷治疗,观察治疗前后患者填写的SF-36、中医临床症状积分、24 hupq、Scr、GFR等指标的变化。结果 A组总有效率为86.7%,B组为66.7%,两组比较差异有统计学意义(P<0.05);A组肾阳虚型、肾阴虚型有效率分别为88.2%、84.6%,B组分别为68.8%、64.3%,两组比较差异有统计学意义(P<0.05);治疗后两组中医症状积分均明显下降(P<0.05),A组差值与B组相比有显著性差异(P<0.05);两组治疗后Scr、24hupq均明显下降,GFR均明显升高,与治疗前相比有显著性差异(P<0.05),治疗后A组与B组在上述指标上有显著性差异(P<0.05);两组治疗后在身体疼痛、一般健康、生命力、社会功能、情感角色、精神健康方面的积分较治疗前提高,且A组积分明显比B组高(P<0.05)。结论保肾巴布剂穴位贴敷疗法能明显改善CKD患者肾功能和临床症状,提高患者生存质量,在常规治疗的基础上,加用保肾巴布剂穴位贴敷治疗CKD肾阳虚型及肾阴虚型有较好的疗效。

ObjectiveTo observe the clinical efficacy of acupoint application withBaoShen cataplasm in treating chronic kidney diseases （CKD） and its effect on the quality of life.MethodSixty CKD patients were randomized into a treatment group and control group, 30 cases in each group. The control group was intervened by conventional Western medicine, while the treatment group was by acupoint application withBaoshen cataplasm in addition to the same Western medicine treatment. The SF-36, symptom score and Chinese medicine, 24hupq, Scr, and GFR were observed before and after intervention.Result The total effective rate was 86.7% in the treatment group versus 66.7% in the control group, and the difference was statistically significant （P〈0.05）; in the treatment group, the effective rates for the kidney yang deficiency and kidney yin deficiency were respectively 88.2% and 84.6%, versus 68.8% and 64.3% in the control group, and the differences were statistically significant （P〈0.05）; the symptom score of Chinese medicine dropped significantly in both groups after intervention （P〈0.05）, while the change in the treatment group was more marked than that in the control group （P〈0.05）; after intervention, the Scr and 24hupq decreased and GFR increased significantly in both groups （P〈0.05）; the bodily pain, general health, vitality, social function, emotional role and mental health scored higher after intervention in both groups, and the scores in the treatment group were significantly higher than that in the control group （P〈0.05）.ConclusionAcupoint Application withBaoshen cataplasm can significantly improve the renal function and symptoms of CKD patients, promote the quality of life, and it can produce a content therapeutic efficacy in treating CKD due to kidney yang deficiency and kidney yin deficiency based on the conventional treatment.