健脾和胃合剂缓解胰腺癌伽玛刀放疗后胃肠道反应的临床观察

The Clinical Efficacy of the Spleen and Stomach Mixture to Ease the Gastrointestinal Reaction of Pancreatic Cancer after Gamma-ray Radiotherapy

目的观察健脾和胃合剂缓解胰腺癌伽玛刀放疗后出现胃肠道反应的临床疗效。方法对60例行伽玛刀放疗的胰腺癌患者进行回顾性分析,采用随机分组法将患者分为实验组和对照组,伽玛刀放疗第1天起,实验组给予肌肉注射胃复安联合口服健脾和胃合剂治疗,对照组给予肌肉注射胃复安治疗。观察伽玛刀放疗过程中和放疗结束后7 d内两组缓解胃肠道反应的临床疗效。结果实验组胃肠道反应总控制率明显高于对照组(P<0.05)。结论健脾和胃合剂具有益气健脾、和胃降逆之功效,能有效缓解胰腺癌伽玛刀放疗后胃肠道反应,改善患者食欲。

Objective： To observe the clinical efficacy of the spleen and stomach mixture to ease the gastrointestinal reaction of pancreatic cancer after gamma-ray radiotherapy. Methods： 60 patients who had received gamma-ray radiotherapy were randomly divided into two groups From the first day of gamma-ray radiotherapy,treatment group were treaded with muscle injection of metoclopramide combined oral the spleen and stomach mix-ture,and the control group were treaded by only muscle injection of metoclopramide. The clinical effect of ease the gastrointestinal reaction were compared between the two groups during radiotherapy within 7 days the end.Results： The total control of the gastrointestinal tract of the treatment group was 88.6%,and the control group was62.3%,two groups of reaction control had significant difference（P 〈0.05）. Conclusion： The spleen and stomach mixture h AS a beneficial good spleen and stomach fall of inverse effect,and can effectively alleviate the gastrointestinal reaction of pancreatic cancer after gamma-ray radiotherapy,and improve appetite.