中西医结合治疗百日咳综合征临床观察

Clinical Observation on Chinese Medicine Integrated with Western Medicine Treatment of 156 Cases of Whooping Cough Syndrome

目的观察中西医结合治疗儿童百日咳综合征的临床疗效。方法将156例百日咳患儿随机分为西医组(序贯使用阿奇霉素或抗病毒药)、西药+中药口服组(口服阿奇霉素和中药)、西药+中药贴治组(口服阿奇霉素和中药贴治)各52例,第1疗程5 d后停4 d,第2疗程3 d后停4 d,观察各组临床疗效,进行成本-效果分析。结果西药+中药口服组总有效率为94.23%,西药+中药贴治组92.31%,西医组96.15%,3者比较无统计学意义(P>0.05),但是中西医结合方法能明显缩短患儿痉咳期的时间,缓解患儿痛楚,并在卫生经济学效益上较西医组有一定优势,更加经济节约。而西药组+中药口服组与西药组+中药贴治组之间在缩短患儿痉咳期的时间和成本方面差异不明显(P>0.05)。结论中西医结合方法治疗儿童百日咳综合征在缩短病程、方便舒适、成本-效果比等方面较单纯使用西医治疗具有一定优势。

Objective： To observe the clinical effects of TCM integrated with Western medicine treating whooping cough syndrome in children. Methods： 156 cases were randomly divided into Western medicine group,Western medicine and TCM decoction group,Western medicine and TCM plaster group,with 52 cases in each group.There were 4 days and 3 days pause after the first and second course respectively. Results： Total effective rates of above three groups were 96.1%,94.2% and 92.3% respectively. The comparison of the three groups had no statistical significance（P 〈0.05）. But TCM integrated with Western medicine treatment could significantly reduce children spasm stage time,relieve the children＇s pain,and has certain advantages in the health economics benefits. In aspects of spasm stage time and cost,Western medicine and TCM decoction group had no statistical difference with Western medicine and TCM plaster group（P 〈0.05）. Conclusion： TCM integrated with Western medicine treating whooping cough syndrome in children has more advantages in the field of disease course,convenience and cost-effectiveness ratio,which is worthy of clinical promotion.