H型高血压患者抑郁患病率及相关因素研究

A study on the prevalence and risk factors of depression among H-type hypertension patients

目的研究H型高血压患者抑郁的患病率及其危险因素,为早期干预提供依据。方法 2013年1月—2014年1月对上海市南京东路社区卫生服务中心收治的H型高血压患者采用抑郁自评量表（SDS）和自行设计的问卷调查抑郁患病率,采用单因素和多因素Logistic回归分析抑郁患病的危险因素。结果 458例H型高血压患者,抑郁患病率为24.45%,男性29.81%高于女性20.00%（P〈0.05）;患病率随年龄增长而升高（P〈0.05）。单因素分析显示,抑郁与非抑郁H型高血压患者的年龄、性别、文化程度、病程、系统治疗、经济状况、家庭支持、合并症和抑郁家族史9个因素差异有统计学意义（P〈0.05）;多因素非条件Logistic回归分析显示,男性（OR=1.99,95%CI 1.65~2.38）、文化程度低（OR=3.77,95%CI 2.93~5.48）与病程长（OR=1.71,95%CI 1.54~1.90）是H型高血压患者抑郁患病的独立影响因素。结论 H型高血压患者的抑郁患病率相对较高,应针对危险因素,开展综合干预。

Objective To learn the prevalence and risk factors of depression among H- type hypertension patients and to provide suggestions for early intervention. Methods Self- rating depression scale（ SDS） and self- designed general condition questionnaire were used to investigate the prevalence of depression,the risk factors of depression among H- type hypertension patients. The data were analyzed by univariate analysis and multivariate logistic regression analysis. Results A total of 458 patients who were admitted to our hospital from Jan,2013 to Jan,2014 were enrolled in this study. Of 458 patients,24. 45%had depression. The prevalence among males was higher than females（ 29. 81% vs 20. 00%,P〈0. 05）,and the prevalence increased with age（ P〈0. 05）. Univariate analysis showed that there were significant differences in age,gender,educational level,family support,complications,courses of disease,systematic therapy,economic conditions and family history of depression between patients with or without depression（ P〈0. 05）. Multivariate logistic regression analysis showed that gender（ OR = 1. 99,95% CI = 1. 65- 2. 38）,educational level（ OR = 3. 77,95% CI = 2. 93- 5. 48） and courses of disease（ OR =1. 71,95% CI =1. 54-1. 90） were independent risk factors of depression. Conclusion The prevalence of depression among H- type hypertension patients is at a high level. It is important to carry out comprehensive intervention for risk factors to prevent depression among patients with H- type hypertension.