网络针灸学:一种挖掘穴位配伍规律及生物学机制的新策略

Network acupuncture: a new strategy to investigate the rules and biological mechanisms of acupiont compatibility

在大规模组学技术的推动下,针灸穴位机制的研究取得了一系列进展。然而,在穴位配伍规律和整体效应方面,仍然缺乏深入研究,有待在方法学上寻求新的突破。网络作为一种强调"联系、整体、系统"的新型研究工具,已经渗透到各学科的前沿研究领域,特别是网络药理学的提出对中药方剂研究起到了极大的推动作用。因此,借鉴中药网络药理学的研究经验,将网络生物学与针灸学进行整合,尝试提出"网络针灸学"的概念,为针灸学在新时期的研究奠定基础。

A great progress on the study of the mechanism of acupuncture has been made with the help of massive omics technology. How- ever, there is little further study on the compatibility regularity and overall effect of acupoints, and a new breakthrough can be sought in methodology. Network, a new research tool emphasizing “connection, entity, system”, has been widely used all over the advanced study; especially the network pharmacology has largely promoted the study of traditional Chinese herbs and formulas. Therefore, learning from network pharmacology on the traditional Chinese herbs, we tried to combine acupuncture with network biology to propose“network acupuncture”, in order to lay foundation of further study on acupuncture in the new period.