愈肠康保留灌肠治疗溃疡性结肠炎60例临床观察

Retention Enema with Yuchangkang in the Treatment of Ulcerative Colitis：Clinical Observation of 60 Cases

为观察愈肠康保留灌肠治疗溃疡性结肠炎的临床疗效，将120例溃疡性结肠炎患者随机分为观察组和对照组，每组各60例。观察组给予愈肠康50ml保留灌肠治疗，对照组给予复方黄柏液50ml保留灌肠治疗，均每日1次，15d为1个疗程，用药2个疗程后，比较两组的总体疗效和肠黏膜病变改善情况。结果显示，观察组总有效率为96．7％，对照组总有效率为90．0％，两组比较差异无统计学意义（P〉0．05）。但肠黏膜病变经治疗后较治疗前均有明显改善，以观察组改善情况更为明显，优于对照组（P〈0．05）。结果表明，愈肠康与复方黄柏液保留灌肠治疗溃疡性结肠炎均有较好的疗效，但愈肠康保留灌肠肠黏膜恢复情况更好。

This study was to observe the clinical effect of ulcerative colitis （UC） treated by retention enema with Yuchangkang （a TCM proved recipe）.The 120 UC patients were divided into observation group and control group randomly, n =60 for each;observation group received retention enema with 50 ml Yuchang- kang, control group did so with 50 ml compound Huangbai solution; for both groups, 1 time/d,a treatment course lasted 15 days;after 2 courses the whole effect and the improved condition about lesion change of intestinal mucosa in both groups were compared.As results,the total effective rate was 96.7% in observation group and 90.0% in control group and there was no statistical difference between both groups（ P 〉0.05） ; but the lesion change became improved significantly after treatment, and observation group was more significant than control group（ P 〈0.05）.Results showed that both above mentioned enema solutions have better effect,but Yuchangkang is more better.