依达拉奉联合醒脑静治疗急性脑出血124例的疗效观察

Efficacy observation of edaravone combining Xingnaojing injection on 124 patients with acute cerebral hemorrhage

目的:研究依达拉奉联合醒脑静对急性脑出血的临床治疗效果。方法:将我院神经内科住院部收治的124例急性脑出血患者作为研究对象,根据治疗方式的不同将其分为观察组和对照组,对照组患者给予醒脑静治疗,观察组患者在对照组的基础上联合依达拉奉治疗,对比分析2组患者治疗前后的总体疗效、血肿情况、神经功能缺损情况以及格拉斯哥GCS昏迷评分。结果:2组患者总有效率比较差异有统计学意义,血肿情况、神经功能评分以及格拉斯哥GCS昏迷评分比较差异有统计学意义。结论:依达拉奉在对急性脑出血的治疗上联合醒脑静,较单一用药临床疗效显著,能够显著改善患者昏迷的情况以及受损神经的功能,促进患者的预后,具有很高的临床使用价值。

Objective：To look into clinical efficacy of Edaravone combining Xingnaojing Injection on acute cerebral hemorrhage.Method：124patients with acute cerebral hemorrhage admitted by department of neurology of this hospital were selected as research subjects.They were divided into the observation group and the control group according to the different methods of treatment.Patients in the control group got Xingnaojing injection treatment,and patients in the observation group combined Edaravone treatment on the basis of treatments to the patients in the control group.Overall efficacy,hematoma,nerve function defect and GCS（glasgow coma score）of patients in two groups before and after treatment were compared.Result：The comparison in total effective rate of patients in two groups hitsχ2=4.5556,the comparison in the hematoma,nerve function score and GCS（glasgow coma score）hits t=45.453 2,8.246 1,3.233 0;Each difference was statistically significant（P0.05）.Conclusion：Edaravone combining Xingnaojing injection delivers more significant clinical efficacy in treating acute cerebral hemorrhage when compared to single medication.It can significantly improve coma condition and damaged nerve function of patients,promot the prognosis of patients,and has great value in clinical use.