参附注射液在肿瘤病人使用异丙酚麻醉诱导期间的循环稳定作用

Stable Effect of Shenfu Injection on Circulation System During Anesthesia Induction with Propofol for Cancer Patients

目的 :观察参附注射液在肿瘤病人使用异丙酚麻醉诱导期间对血流动力学的影响。方法 :选择乳腺及头颈部肿瘤手术病人 30例 ,随机分为 2组 ,S组于麻醉诱导前静脉注射参附注射液 0 8ml kg(参附组 ,n =15 ) ,P组麻醉诱导前静脉注射乳酸林格氏液 0 8ml kg(异丙酚组 ,n =15 ) ,5分钟后麻醉诱导 ;两组均静脉注射维库溴铵0 12mg kg ,芬太尼 2 μg kg ,异丙酚 2mg kg麻醉诱导。于麻醉前静息状态下、诱导即刻、插管后即刻、插管后 1分钟、2分钟、3分钟、5分钟、10分钟分别测定收缩压 (SBP)、舒张压 (DBP)、心率 (HR)并记录。结果 :S组患者在麻醉诱导及插管时血流动力较为稳定 ,并且情况优于P组。结论

Objective: To study the effect of Shenfu injection on hemodynamics during anesthesia induction with propofol for cancer patient.Methods:Thirty adult ASA grade Ⅰ Ⅱ patients undergoing elective operation for mammary gland or Head and Neck Oncologcal surgery were divided into two groups:group S Shenfu 0.8ml/kg were injected before anesthesia induction(Shenfu group, n=15 ),5 min later anesthesia was induced.For both groups anesthesia was induced with vecuronim 0.12mg/kg,fentany12 μg/kg,propofol 2mg/kg.The SBP,DBP,HR were measured and recorded at the static state,before anesthesia induction,and the beginning of the anesthesia induction and 1,2,3,5,10min after trachea intubation.Results:Stables effect of Shenfu injection on circulation system during the anesthesia induction was obserred in groups S than that group.Conclusions:Shenfu injection may effectively keep the stability of circulation system during the anesthesia induction with propofol for cancer patient.