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非小细胞肺癌单发脑转移患者手术治疗效果观察 被引量:3

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摘要 目的:探讨手术联合放化疗治疗非小细胞肺癌单发脑转移患者手术治疗的临床效果。方法将67例非小细胞肺癌同时单发脑转移的患者随机分为观察组34例和对照组33例。对照组行放疗联合吉西他滨、替莫唑胺化疗。观察组在对照组基础上行肺部肿瘤切除及脑转移瘤切除术。对比观察2组生存期和生存率。结果观察组死亡28例,存活6例。对照组死亡32例,存活1例。观察组生存期为6.8~39.4(19.64±1.68)个月。对照组生存期为4.7~38.2(16.00±1.58)个月。2组生存期差异有统计学意义(X2=9.756,P=0.002,<0.01)。观察组1年生存率为97.1%(33/34),2年生存率为35.3%(12/34),3年生存率为17.6%(6/34),对照组1年生存率为69.7(23/33)%,2年生存率为18.18%(6/33),3年生存率为6.01%(2/33),2组生存率差异有统计学意义(P<0.05)。结论手术切除肺部原发肿瘤及脑转移瘤对改善非小细胞肺癌单发脑转移患者的预后具有一定作用。
出处 《临床合理用药杂志》 2015年第4期145-146,共2页 Chinese Journal of Clinical Rational Drug Use
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