5-甲基水杨醛缩对氨基水杨酸希夫碱镍配合物的合成、表征及其性质研究

5-Bethyl-salicylaldehyde-4-aminosalicylicacid Schiff base nickel complexes:synthesis,characterization and properties

本文以5-甲基水杨醛和对氨基水杨酸为原料合成希夫碱配体,该配体与Ni2+作用得到了5-甲基水杨醛缩对氨基水杨酸镍配合物,通过紫外吸收法、元素分析、红外光谱法对其结构进行表征,并通过EDTA滴定法确定了配合物的金属含量。用荧光光谱法研究了该化合物对牛血清白蛋白荧光光谱的影响,根据荧光猝灭效应Stern-Volmer方程和双对数回归模型计算该化合物和牛血清白蛋白在不同温度下的结合常数和结合位点数。

Synthetic the nichel complexe of Schiff base of 5-Bethyl-salicylaldehyde-4-aminosalicylicacid,which was characterized by UV-Vis,IR,elemental analysis,and by EDTA titration method to determine the metal content of complexes. The interaction between Schiff base complex and bovine serum albumin（BSA）was studied by fluorescence spectra. The use of Stern-Volmer equation,double logarithm regression equation of florescence spectroscopy data,the binding constants,the number of binding sites and the relative thermodynamic parameters of complex with BSA were obtained in the different temperature.