摘要
长链非编码RNA(lncRNA)是一类长度大于200个核苷酸,但并不具备编码蛋白质功能的基因转录产物。lncRNA在细胞增殖、分化、衰老、死亡及肿瘤的发生发展中发挥重要作用。文章就lncRNA的主要特点及其对肿瘤耐药作用的研究进展作一综述。
Long non-coding RNA (lncRNA) is a group of length more than 200 nucleotides without coding protein RNA. It plays an important role in cell proliferation, differentiation, senescence, death, tumor occurrence and development. This article reviews the main characteristics of lncRNA and its role in tumor drug resistance.
出处
《肿瘤研究与临床》
CAS
2015年第1期69-72,共4页
Cancer Research and Clinic