3种血清心肌标志物联合检测在急性心肌梗死诊断中的应用

目的探讨3种血清心肌标志物联合检测在急性心肌梗死诊断中的应用。方法选取急性心肌梗死患者43例作为观察组;选取普通冠心病患者43例作为对照组;选取进行体检的健康体检者的血液样本43例作为空白对照组。对每组成员的Mb、c Tc I、CK-MB进行检测、统计学分析及评价。结果观察组患者血清中Mb、c Tn I、CK-MB水平均高于对照组及空白对照组,差异有统计学意义(P<0.05)。结论血清Mb是急性心肌梗死诊断中具有敏感性、特异性的生化指标,血清中Mb、c Tn I、CK-MB的联合检测对于急性心肌梗死的早期诊断及鉴别诊断,具有重要的临床意义。

Objective To explore three kinds of combined detection of serum cardiac markers in the diagnosis of acute myocardial infarction. Methods Choose from 43 patients in our hospital with acute myocardial infarction Cardiology treated as the observation group. Select Normal coronary heart disease 43 cases as a control group. Extraction in our hospital for medical examination of 43 cases of healthy blood samples as a control group. Members of each serum Mb,cTcI,CK-MB were detected, statistical analysis and the evaluation. Results The serum of patients in the observation group Mb, cTnI, CK-MB levels were higher and the control group, and （P〈0.05） difference was statistically signiifcant. Conclusion Serum Mb diagnosis of acute myocardial infarction with a sensitivity and speciifcity of biochemical markers, serum Mb, cTnI, CK-MB, the joint detection for early diagnosis and differential diagnosis of acute myocardial infarction has important clinical signiifcance.