摘要
目的:观察补肾温心汤治疗慢性收缩性心力衰竭心肾阳虚证的临床疗效。方法:将60例患者随机分为治疗组和对照组两组,每组30例。对照组在一般治疗基础上服用利尿剂、血管紧张素转化酶抑制剂、β受体阻滞剂,必要时予地高辛。治疗组在对照组治疗的基础上加服补肾温心汤150m L/次,2次/d,4周为1个疗程。观察两组治疗前后心功能疗效、心衰疗效、中医证候疗效及LVEF的变化。结果:1两组患者治疗后心功能疗效、心衰疗效、中医证候疗效均优于治疗前,具有显著性差异(P<0.05);两组间治疗后比较,心功能疗效、心衰疗效、中医证候疗效均显示治疗组优于对照组,具有显著性差异(P<0.05)。2治疗后两组均可以明显改善LVEF,有显著性差异(P<O.05);两组间治疗后比较也有显著性差异(P<0.05)。结论:补肾温心汤配合西药治疗慢性收缩性心力衰竭心肾阳虚证与单独应用西药治疗相比,能更有效地改善心衰症状、体征,改善中医证候,提高心功能,改善LVEF。
Objective:To observe clinical curative effects of the Bushen Wenxin decoction on chronic systolic heart failure with Xinshen Yangxu. Methods:60 patients were randomly divided into treatment group and control group. On the basis of general treatment, the control group was given the diuretic, angiotensin-converting enzyme inhibitors, β-receptor blocker and digoxin when necessary; the treatment group was added the Bushen Wenxin decoction 150mL, twice a day, for 4 weeks. To observe the curative effect of cardiac function, the curative effect of heart failure, the curative effect of syndromes of TCM and the change of LVEF before and after treatment in two groups. Results: I The curative effect of cardiac function, heart failure, and syndromes of TCM in two groups after treatment were superior than that before treatment, with significant difference, and the treatment group was better (P〈0.05). II The LVEF in the two groups can be significantly improved after treatment, with significant difference (P〈0.05); difference in two groups with significant difference (P〈0.05). Conclusion:Compared with western medicine, the Bushen Wenxin decoction plus western medicine can effectively improve the symptoms, signs of heart failure, syndromes of TCM, cardiac function and LVEF.
出处
《中医临床研究》
2014年第31期10-11,20,共3页
Clinical Journal Of Chinese Medicine