西宁市1541例门诊患者空腹血糖和糖化血红蛋白状况及相关性分析

Correlation Analysis Between Fasting Plasma Sugar and Glycated Hemoglobin in 1541 Outpatients at Xining Area

目的:探讨西宁市部分门诊患者就诊时血糖状况,分析其空腹血糖(FPG)和糖化血红蛋白(GHb A1c)间相关性。方法:选取我院2013年1月1—2013年6月30日同时化验FPG和GHb A1c的门诊患者1 541例,按就诊疾病及人群不同进行分类统计FPG和GHb A1c值,并检测两者的相关性。结果:患者FPG均值(8.7±4.5)mmol/L,≥7.0mmol/L占51.5%(794/1 541);GHb A1c均值(7.4±3.4)%,≥6.5%占45.6%(702/1 541)。糖尿病(DM)患者FPG和GHb A1c均值分别为(10.9±4.7)mmol/L、(9.2±3.4)%,非DM患者(6.2±2.5)mmol/L、(5.5±2.0)%,差异均有统计学意义(P<0.01)。DM患者FPG≥7.0mmol/L和GHb A1c≥6.5%分别为79.3%(635/801)和70.3%(563/801),非DM患者为21.2%(159/740)和18.8%(139/740),差异均有统计学意义(P<0.01)。FPG对GHb A1c总体相关系数(r)=0.64(P<0.01),DM患者r=0.49(P<0.01),非DM患者r=0.53(P<0.01),体检人员r=0.83(P<0.01)。结论:西宁市部分就诊人员血糖状况堪忧,以DM患者为甚;FPG和GHb A1c相关性在器质性疾病患者中不明显,而与体检人员中相关性较好。

Objective： To investigate the correlation between fasting plasma glucose（ FPG） and glycated hemoglobin A1c（ GHb A1c） in outpatients at Xining area.Methods： FPG and GHb A1 c were detected in 1 541 outpatients from January 1 to June 30 in 2013.Data were collected according to different diseases and groups and correlation analysis were carried out between FPG and GHb A1 c.Results： The ensemble average of FPG and GHb A1 c were（ 8.7 ± 4.5） mmol / L and（ 7.4 ± 3.4） %,respectively.the proportion of FPG≥7.0mmol / L and GHb A1c≥6.5% were 51.5%（ 794 /1 541） and 45.6%（ 702 /1 541）,respectively.The significant difference of mean values of FPG and GHb A1 c were observed between the diabetic patients and non- diabetic patients（ 10.9 ± 4.7） mmol / L vs（ 6.2 ± 2.5） mmol / L,respectively,P〈0.01;（ 9.2 ± 3.4） % vs（ 5.5 ± 2.0） %,P〈0.01,respectively.Compared with the diabetic patients,the proportion of FPG≥7.0 mmol / L and GHb A1c≥6.5% were lower in non- diabetic patients79.3%（ 635 /801） vs 21.2%（ 159 /740）,P〈0.01; 70.3%（ 563 /801） vs 18.8%（ 139 /740）,P〈0.01.The correlation coefficient of total group between FPG and GHb A1 c was 0.64（ P〈0.01）.And correlation coefficient in diabetic patients,non- diabetic patients and physical examination people were 0.49,0.53,0.83（ P〈0.01）,respectively.Conclusions： The situation of blood sugar is of concern in outpatients in Xining,especially in diabetic patients.the correlation between FPG and GHb A1 c is well in physical examination people,but not in patients with organic disease.