期刊文献+

尿钙及尿钙/尿肌酐比值诊断子痫前期的价值 被引量:1

下载PDF
导出
摘要 目的探讨24 h尿钙、尿钙/尿肌酐比值、尿钙/血钙对子痫前期的诊断价值。方法对80例子痫前期孕妇(轻度子痫前期组48例,重度子痫前期组32例)和180例正常妊娠孕妇的尿液和血液进行检验,并通过受试者工作特征曲线比较24 h尿钙、尿钙/尿肌酐比值、尿钙/血钙对子痫前期的诊断价值。结果 24 h尿钙、尿钙/尿肌酐比值和尿钙/血钙比值的曲线下面积分别为0.848,0.895,0.840。24 h尿钙、尿钙/尿肌酐比值和尿钙/血钙比值分别在取值110.1 mg/24 h、0.08 mg/mg和1.25 mmol/mmol时敏感度和特异度分别为96.3%和70.6%、98.8%和74.4%、93.8%和70.6%。结论 24 h尿钙、尿钙/尿肌酐比值及尿钙/血钙比值在子痫前期孕妇中均降低,可以作为诊断子痫前期的指标,尿钙/尿肌酐比值可能比24 h尿钙更加可靠。
出处 《广东医学》 CAS CSCD 北大核心 2014年第19期3048-3051,共4页 Guangdong Medical Journal
  • 相关文献

参考文献13

  • 1VON DADELSZEN P, MAGEE L A. Pre - eclampsia : An Update [J]. Curr Hypertens Rep, 2014, 16(8) : 454.
  • 2VOGEL J P, SOUZA J P, MORI R, et al. Maternal complications and perinatal mortality : findings of the World Health Organization Muhieountry Survey on Maternal and Newborn Health [ J ]. B JOG, 2014, 121 Suppl 1 : 76 -88.
  • 3HUTCHEON J A, LISONKOVA S, JOSEPH K S. Epidemiology of pre -eclampsia and the other hypertensive disorders of pregnancy [J]. Best Pratt Res Clin Obstet Gynaecol, 2011, 25(4) : 391 - 403.
  • 4SZPERA GOZDZIEWICZ A, BREBOROWICZ G H. Endothelial dysfunction in the pathogenesis of pre - eclampsia[ J]. Front Bios- ci (Landmark Ed), 2014, 19 : 734 - 746.
  • 5邬俏璇,王晨虹.妊娠期高血压疾病病因相关因子研究概况[J].医学综述,2013,19(13):2318-2321. 被引量:8
  • 6YANG H, KIM T H, AN B S, et al. Differential expression of cal- cium transport channels in placenta primary cells and tissues de- rived from preeclamptic placenta[ JJ. Mol Cell Endocrinol, 2013, 367(1/2) : 21 -30.
  • 7SEGOVIA B L, VEGA I T, VILLARREAL E C, et al. Hypocalci- uria during pregnancy as a risk factor of preeclampsia[J]. Ginecol Obstet Mex, 2004, 72 : 570 - 574.
  • 8VILLAR J, ABDEL ALEEM H, MERIALDI M, et al. World Health Organization randomized trial of calcium supplementation a- mong low calcium intake pregnant women[J]. Am J Obstet Gyne- col, 2006, 194(3): 639-649.
  • 9SZMIDT ADJIDI~ V, VENDITIELLI F, DAVID S, et al. Calci- uria and preeclampsia : a case - control study [J]. Eur J Obstet Gynecol Reprod Biol, 2006, 125 (2) : 193 - 198.
  • 10GASNIER R, VALI~RIO E G, VETTORAZZI J, et al. Calciuria and preeclampsia: a case - control study [ J ]. J Obstet Gynaecol Res, 2012, 38(4) : 674 -680.

二级参考文献29

  • 1赵茵,邹丽,杨昀.内皮型一氧化氮合酶基因多态性与妊娠期高血压疾病的相关性研究[J].实用医学杂志,2005,21(3):252-254. 被引量:2
  • 2周从容,邬卫东,马俊如.妊娠高血压综合征患者血清中可溶性Fas水平的测定及其临床意义[J].贵州医药,2005,29(6):489-490. 被引量:1
  • 3卢丽萍,卢杰平,潘莉莉,李强,刘长丽.妊娠高血压综合征患者胎盘滋养细胞线粒体ATP酶和氧自由基变化的研究[J].中国现代医学杂志,2006,16(18):2782-2784. 被引量:6
  • 4Tosun M,Celik H,Avci B,et al.Maternal and umbilical serum lev-els of interleukin-6,interleukin-8,and tumor necrosis factor-alpha innormal pregnancies and in pregnancies complicated by preeclampsia[J].J Matern Fetal Neonatal Med,2010,23(8):880-886.
  • 5Kumpel BM,Manoussaka MS.Placental immunology and maternalalloimmune responses[J].Vox Sang,2012,102(1):2-12.
  • 6Molvarec A,Shiozaki A,Ito M,et al.Increased prevalence ofperipheral blood granulysin-producing cytotoxic T lymphocytes inpreeclampsia[J].J Reprod Immunol,2011,91(1/2):56-63.
  • 7Longtine MS,Nelson DM.Placental dysfunction and fetal program-ming:the importance of placental size,shape,histopathology,andmolecular composition[J].Semin Reprod Med,2011,29(3):187-196.
  • 8Forbes K,Westwood M,Baker PN,et.al.Insulin-like growth factorI and II regulate the life cycle of trophoblast in the developinghuman placenta[J].Am J Physiol Cell Physiol,2008,294(6):C1313-C1322.
  • 9Hills FA,Elder MG,Chard T,et al.Regulation of human viiloustrophoblast by insulin-like growth factor-binding protein-1[J].JEndocrinol,2004,183(3):487-496.
  • 10Galewska Z,Bańkowski E,Romanowicz L,et al.Pre-eclampsia(EPH-gestosis)-induced decrease of MMP-s content in the umbili-cal cord artey[J].Clin Chim Acta,2003,335(1/2):109-115.

共引文献7

同被引文献14

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部