期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

氯诺昔康联合曲马多对胃癌根治术患者术后血浆细胞因子的影响 被引量：5

下载PDF
导出
摘要 术后疼痛常引起患者心血管、神经内分泌及免疫等系统功能的紊乱。阿片类药物是临床应用最广泛的术后镇痛药,但其具有免疫抑制等不良反应[1,2]。非甾体抗炎药（NSAIDs）氯诺昔康具有良好的镇痛和抗炎作用,但单独应用于腹部等大手术,无法有效缓解疼痛,因此常须与阿片类药物或曲马多合用[3,4]。
作者 谷新荣 王灿琴 王忠云 钱燕宁
机构地区 江苏省新沂市人民医院麻醉科 南京医科大学第一附属医院麻醉科
出处 《临床麻醉学杂志》 CAS CSCD 北大核心 2014年第10期1033-1035,共3页 Journal of Clinical Anesthesiology
关键词 氯诺昔康 阿片类药物 术后镇痛药 细胞因子 免疫抑制 术后疼痛 根治术 昂丹司琼 非甾体抗炎药 临床应用
分类号 R614 [医药卫生—麻醉学] R735.2 [医药卫生—肿瘤]
  • 相关文献

参考文献9

  • 1Filipczak-Bryniarska I, Nowak B, Sikora E, et al. The influ- ence of opioids on the humoral and cell-mediated immune re- sponses in mice. The role of macrophages. Pharmacol Rep, 2012, 64(5): 1200-1215.
  • 2沈锦春,郭海峰,杨建军,段满林,朱四海,徐建国.氟比洛芬酯联合吗啡镇痛对胃癌患者术后吗啡用药量及肠功能恢复的影响[J].临床麻醉学杂志,2009,25(5):383-386. 被引量：38
  • 3Arslan M, Tuncer B, Babacan A, et al. Postoperative analge- sic effects of lomoxicam after thyroidectomy: a placebo con- trolled randomized study. Agri, 2006, 18(2): 27-33.
  • 4Mowafi HA, Elmakarim EA, Ismail S, et al. Intravenous lor- noxieam is more effective than paraeetamol as a supplemental analgesic after lower abdominal surgery: a randomized con- trolled trial. World J Surg, 2012, 36(9) 2019-1044.
  • 5Sheeran P, Hall GM. Cytokines in anaesthesia. Br J Anaesth, 1997, 78(2): 201-219.
  • 6Raeburn CD, Sheppard F, Barsness KA, et al. Cytokines for surgeons. Am J Surg, 2002, 183(3) : 268-273.
  • 7Cevik E, Cinar O, Salman N, et al. Comparing the efficacy of intravenous tenoxicam, lornoxicam, and dexketoprofen tro- metamol for the treatment of renal colic. Am J Emerg Med,2012, 30(8): 486-1490.
  • 8Nagahiro I, Andou A, Aoe M, et al. Pulmonary function, postoperative pain, and serum cytokine level after lobectomy.. a comparison of VATS and conventional procedure. Ann Tho- rac Surg, 2001, 72(2), 362-365.
  • 9Shirzad H, Shahrani M, Rafieian-Kopaei M. Comparimn of mor- phine and tramadol effects on phagocytic activity of mice peritoneal phagocytes in vivo. Int Immunopharmacol, 2009, 9 (7-8) 968-970.

二级参考文献10

  • 1Yamashita K,Fukusaki M,Ando Y,et al.Preoperative administration of intravenous flurbiprofen axetil reduces postoperative pain for spinal fusion surgery.J Anesth,2006,20:92-95.
  • 2Ohmukai O.Lipo-NSAID preparation.Adv Drug Deliv Rev,1996,20:203-207.
  • 3Xu Y,Tan Z,Chen J,et al.Intravenous flurbiprofen axetil accelerates restoration of bowel function after colorectal surgery.Can J Anaesth,2008,65:414-422.
  • 4Reuben SS,Connelly NR.Postoperative analgesic effects of celecoxib or rofecoxib after spinal fusion surgery.Anesth Analg,2000,91,1221-1225.
  • 5Malmstrom K,Daniels S,Kotey P,et al.Comparison of rofecoxib and celecoxib,two cyclooxygenase-2 inhibitors,in postoperative dental pain:a randomized,placebo-and activecomparator-controlled clinical trial.Clin Ther,1999,21:1653-1663.
  • 6Takada M,Fukusaki M,Terao Y,et al.Preadministration of flurbiprofen suppresses prostaglandin production and postoperative pain in orthopedic patients undergoing tourniquet inflation.J Clin Anesth,2007,19:97-100.
  • 7Roszkowski MT,Swift JQ,Hargreaves KM.Effect of NSAID administration on tissue levels of immunoreactive prostaglandin E2,leukotriene B4,and (S)-flurbiprofen following extraction of impacted third molars.Pain,1997,73:339-345.
  • 8Parepally JM,Mandula H,Smith QR,et al.Brain Uptake of Nonsteroidal Anti-Inflammatory Drugs:Ibuprofen,Fhirbiprofen,and Indomethacin.Pharm Res,2006,23:873-881.
  • 9Bannwarth B,Netter P,Pourel J,et al.Clinical pharmacokinetics of nonsteroidal anti-inflammatory drugs in the cerebrospinal fluid.Biomed Pharmacother,1989,43:121-126.
  • 10Nakayama M,Ichinose H,Yamamoto S,et al.Perioperative intravenous flurbiprofen reduces postoperative pain after abdominal hysterectomy.Can J Anaesth,2001,48:234-237.

共引文献37

同被引文献42

  • 1唐人,熊剑勇,刘丹,李其云,易波.低分子肝素对老年胃癌根治术患者的氧化应激反应及肾功能的影响[J].中国生化药物杂志,2014,34(3):74-77. 被引量：20
  • 2Batista LM, Batista IM, Almeida JP, et al. Preemptive analgesic effect of lidocaine in a chronic neuropathic pain model [ J ]. Arq Neuropsiquiatr,2009,67 ( 4 ) : 1088 - 1092.
  • 3Mowafi HA, Elmakarim EA, Lsmail S,et al. Intravenous lomoxicam is more effective than paracetamol as a supplemental analgesic after lower abdominal surgery : a randomized controlled trail [ J ]. World J Surg,2012,36(9) :2039 -2044.
  • 4Ghilardi JR, Svensson CI, Rogers SD. Constitutive spinal cyelooxygenase-2 participates in the initiation of tissue injury- induced hyperalgesia[ J ]. J Neurosci ,2004 ,24( ll ) :2727 -2732.
  • 5VAISH V, PIPLANI H, RANA C, et al. }<SAIDs may regulate EGR-l-mediated induction of reactive oxygen species and non-steroidal anti-inflammatory drug- induced gene(NAG)-i to initiate intrinsic pathway of apoptosis for the chemoprevention of colorectal cancer [J]. Mol Cell Biochem, 2013, 378:47--64.
  • 6JUNG S K, SU J H, KIM Y A, et al. MLK3 is a novel target of dehydroglyasperin D for the reduction in UVB-indueed COX-2 expression in vitro and in vivo. [J]. J Cell Mol Med, 2015, 19 135--142.
  • 7HARN H J, CHUANG H M, CHANG L F, et al. Taiwanin A targets non-steroidal anti-inflammatory drug-activated gene-1 in human lung carcinoma[J]. Fi- toterapia, 2014, 99 .227--235.
  • 8MA R, YI B, PIAZZA G A, et al. Mechanistic Role of MicroRNA in Cancer Chemoprevention by Nonsteroi- dal Anti-inflammatory Drugs[J]. Cur Pharmacol Rep, 2015, 1.1--7.
  • 9SAHIN I H, HASSAN M M, GARRETT C R. Impact of non-steroidal anti-inflammatory drugs on gastroin- testinal cancers:current state of-the science[J]. Cancer Lett, 2014, 345:249--257.
  • 10SATO T, KIMOTO N, OHKI Y, et al. Methods for screening of patient to be administered with pharma- ceutical agent comprising anti-cancer antibody as active ingredient:EP, US8642032[P]. 2014.

引证文献5

二级引证文献20

临床麻醉学杂志
2014年 第10期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部