消旋卡多曲治疗急性腹泻的效果分析

Effect Analysis of Racecadotril in the Treatment of Acute Diarrhea

目的观察消旋卡多曲治疗成人急性腹泻的治疗效果,探讨消旋卡多曲治疗急性腹泻的临床应用价值。方法以2012年1月至2014年1月间我院急诊科收治的100例成人急性腹泻患者为研究对象,按照随机分组的原则将所有患者随机分为观察组和对照组各50例接受治疗。对照组患者采用WHO标准化口服补液治疗以纠正患者水电解质代谢紊乱和酸碱失衡,观察组患者在对照组患者治疗基础上加用消旋卡多曲。对比两组患者的治疗效果,以明确消旋卡多曲在成人急性腹泻治疗中的作用。结果经过治疗,观察组治疗有效率为96.00%,高于对照组的84.00%,差异有统计学意义(P<0.05);治疗过程中,观察组患者每天大便次数少于对照组,大便性质恢复时间、水电解质代谢恢复正常时间、治疗时间均短于对照组,差异有统计学意义(P<0.05)。结论常规治疗基础上加用消旋卡多曲治疗急性腹泻,可迅速缓解患者病情,缩短病程。

Objective To observe and investigate the therapeutic effect and clinical value of racecadotril in treating acute diarrhea in adults. Methods 100 cases of patients with acute diarrhea treated in our emergency department from January 2012 to January 2014 were selected as objects and randomly divided into observation group and control group, with 50 cases in each group. The control group was given with WHO standardized oral rehydration therapy to correct the water electrolyte metabolic disturbance and acid-base imbalance, and the observation group received racecadotril on the basis of the control group. The therapeutic effect was compared in order to clarify the role of racecadotril in treating acute diarrhea in adults. Results After treatment, the effective rate of the observation group was 96.00%, higher than 84.00%of the control group, with statistical significant difference （P 〈0.05）;the shit times of the observation group everyday was shorter than that of the control group, and the recovery time of shit nature and water electrolyte metabolism, the treatment time of the observation group was shorter than that of the control group, with statistical significant difference （P〈0.05）. Conclusions The application of racecadotril in treating acute diarrhea in adults on the basis of conventional treatment can quickly relieve patients＆#39; disease conditions and shorten the course of disease.