血清孕酮和β-HCG检测在异位妊娠早期诊断中的应用价值

Serum Progesterone and β-HCG Test Application Value in Early Diagnosis of Ectopic Pregnancy

目的研究血清孕酮和β-HCG检测在异位妊娠早期诊断中的应用价值。方法选取我院2013年1月至2014年1月接收的35例正常妊娠的孕妇作为对照组以及35例异位妊娠孕妇作为观察组。分别检测两组的血清孕酮和β-HCG的含量,4至6周后对两组妇女的血清孕酮和β-HCG含量的变化进行比较。结果第4周观察组的β-HCG含量与对照组比较显著差异(P>0.05),观察组孕酮含量明显低于对照组(P<0.05);第5、6周观察组孕酮含量和β-HCG含量均明显低于对照组(P<0.05),对血清孕酮以及β-HCG含量进行联合检测的符合率明显高于单独对β-HCG含量测定,并且可以明显减少确诊时间(P<0.05)。结论早期进行血清孕酮和β-HCG联合检测能够减少异位妊娠确诊时间,降低漏诊与误诊发生率,值得临床借鉴和推广。

Objective To study the value of the detection of serum progesterone andβ-HCG in early diagnosis of ectopic pregnancy. Methods 35 cases of normal pregnancy women treated in our hospital from January 2013 to January 2014 were selected as control group, and 35 cases of ectopic pregnancy women were selected as observation group. The content of serum progesterone andβ-HCG of two groups were detected, and the content changes of serum progesterone and β-HCG of two groups were compared after 4 weeks, 5 weeks and 6 weeks. Results After 4 weeks, the β-HCG content of the observation group had no statistical significant difference compared with the control group （P〉0.05）, the progesterone content of the observation group was significantly lower than that of the control group （P〈0.05）;after 5 weeks and 6 weeks, the progesterone content and theβ-HCG content of the observation group were significantly lower than those of the control group （P 〈0.05）, the coincidence rate of the joint detection of the serum progesterone content and β-HCG content was significantly higher than that of the solo detection of the β-HCG content （P 〈0.05）, which could obviously reduce the diagnosis time. Conclusions The early joint detection of serum progesterone and β-HCG can reduce the diagnosis time of ectopic pregnancy, reduce missed diagnosis and misdiagnosis, which is worthy of reference and promotion.