中药辅助治疗支气管哮喘急性发作50例疗效观察

Clinical observation on effect of TCM decoction on 50 patients with acute bronchial asthma

目的探讨射干麻黄汤联合小青龙汤辅助治疗支气管哮喘急性发作的临床疗效。方法选取2012年1月至2014年1月收治的支气管哮喘患者100例,随机分为观察组和对照组,每组50例。对照组患者予常规西医治疗。观察组患者在同对照组患者治疗的基础上加用射干麻黄汤联合小青龙汤辅助治疗。2周后比较两组患者的临床疗效以及两组患者治疗前后FEV1、FVC、PEF及中医症候积分的变化。结果观察组患者治疗总有效率(96.0%)显著高于对照组患者(78.0%),两组比较差异有统计学意义(P<0.01),秩和检验结果显示观察组患者临床疗效显著优于对照组患者(P<0.05)。治疗后两组患者的FEV1、FVC、PEF均较治疗前显著升高,且观察组患者的FEV1、FVC、PEF明显高于对照组患者,差异有统计学意义(P<0.01)。治疗后两组患者的中医症候积分均较治疗前明显降低,观察组患者治疗后的中医症候积分显著低于对照组,差异有统计学意义(P<0.01)。结论射干麻黄汤联合小青龙汤辅助治疗支气管哮喘急性发作能明显提高疗效,明显改善患者的临床症状及肺功能,值得推广和应用。

Objective To investigate the efficacy of Sheganmahuang decoction combined with Xiaoqinglong decoction on patients with acute bronchial asthma. Methods 100 patients with bronchial asthma who were admitted to our hospital from January2012 to January 2014 were randomly divided into observation group and control group,with 50 cases in each. The control group received western medicine,while the observation group received Sheganmahuang decoction and Xiaoqinglong decoction for adjuvant therapy based on western medicine. the treatment lasted for 2 weeks,the FEV1,FVC,PEF and symptom scores in two groups before and after treatment were compared. Results Total effective rate of observation group and control group was 96% and 78%,respectively,there was significant difference between the two groups（ P〈0. 01）,the rank sum test results showed that the clinical curative effect of the observation group was significantly better than that of control group（ P〈0. 01）. After treatment,the FEV1,FVC,PEF in both groups were significantly higher than those before treatment,and all indexes in the observation group were significantly higher than those in the control group（ P〈0. 05）. Symptom scores in both groups was significantly lower than that before treatment,and the observation group improved more obviously（ P〈0. 05）. Conclusion Sheganmahuang decoction combined with Xiaoqinglong decoction for adjuvant treatment can increase therapeutic effect and improve lung function in patients with acute bronchial asthma,which is worthy to be widely emplyed.