Th17、IL-17与中枢神经系统相关疾病的研究进展

Th17/IL-17 and associated central nervous system diseases:research advances

在适应性免疫应答中,CD4+T细胞发挥着重要的调节作用,与Th1、Th2细胞不同,新近发现的Th17细胞通过其特征性细胞因子IL-17在自身免疫性疾病、炎症反应、移植排斥反应及中枢神经系统疾病中均发挥重要作用。本文就Th17细胞及IL-17与中枢神经系统疾病的关系做一综述。

The CD4＋T cells have an important effect on the regulation of the adaptive immune response. Unlike Th1 cells and Th2 cells,this newly-found Th17 cell plays an important role in autoimmune diseases,inflammation response,transplant rejection and central nervous system disease by the cytokine IL-17. This paper gives a brief review on the relationship among the Th17 cell,the cytokine IL-17 and the disease of central nervous system.