妊娠合并梅毒母亲所生新生儿42天听力复筛结果分析

42-days hearing screening results in newborns whose mother with syphilis

目的探讨妊娠合并梅毒母亲所生新生儿42天听力复筛结果是否受母体梅毒感染因素的影响。方法采用畸变产物耳声发射测试,对母亲妊娠合并梅毒的新生儿进行42天听力复筛。结果疑似先天性梅毒儿46例,其中梅毒螺旋体颗粒凝集试验(TPPA)单阳性者18例,占39.13%,全部通过42天听力复筛;梅毒血清反应素试验(RPR)/TPPA双阳性者28例,占60.87%,其中27例通过42天听力复筛;42天听力复筛总通过率为97.83%。未通过听力复筛1人,该儿童双耳听性脑干反应阈值(ABR)均通过听力诊断检查。结论疑似先天性梅毒儿的听力在新生儿阶段没有受母体梅毒感染的影响。

Objective To explore whether the infective factor will affect the results of 42- days hearing screening in newborns whose mother with syphilis. Methods 42- days hearing screening was performed in all the infants born to mothers with syphilis using distortion product otoacoustic emissions（ DPOAE）. Results Of 46 latent syphilis newborns,18（ 39. 13%） showed positive result for Treponema pallidum particle agglutination（ TPPA） test,and all of them passed 42- days hearing screening; 28（ 60. 87%） showed positive results for both TPPA and rapid plasma reagin（ RPR） test,and 27 of them passed 42- days hearing screening. The total rate of passing 42- days hearing screening was 97. 83%. One case failed in the 42- days hearing screening,but passed in auditory brainstem responses（ ABR） test. Conclusion This study suggests no effect of mothers＇ syphilis on the hearing of suspected congenital syphilis newborns in neonatal period.