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贝那普利、美托洛尔联合螺内酯治疗老年舒张性心力衰竭的疗效与安全性 被引量:11

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摘要 目的观察贝那普利、美托洛尔与螺内酯联合应用治疗老年舒张性心力衰竭(DHF)的临床疗效与安全性。方法入选老年DHF患者68例,根据住院顺序编号,按照随机数字表法随机分为试验组(n=36)和对照组(n=32)。对照组采用常规治疗;试验组加用贝那普利、美托洛尔及螺内酯,平均剂量分别为16.8 mg/d、46.4 mg/d、26.8mg/d。2组疗程均6个月。在治疗前后检测B型钠尿肽原(NT-BNP),测定6 min步行试验。结果治疗后试验组6min步行距离(557±71)m,较治疗前的(371±81)m明显改善(P<0.01);与对照组(478±83)m比较差异有统计学意义(P<0.01)。2组治疗后NT-BNP均较治疗前明显降低,并且试验组显著优于对照组(P<0.01)。结论贝那普利、美托洛尔与螺内酯联合治疗老年DHF,可以改善患者心脏舒张功能,提高活动耐量,并且具有良好的安全性。
出处 《现代中西医结合杂志》 CAS 2014年第31期3472-3474,共3页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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参考文献13

  • 1刘春霞,陈明.舒张性心力衰竭的发病机制和治疗进展[J].心血管病学进展,2013,34(2):254-257. 被引量:42
  • 2中国心力衰竭诊断和治疗指南2014[J].中华心血管病杂志,2014,42(2):98-122. 被引量:4661
  • 3杨玉恒,戴向军,李更新,薛润发,李强.依那普利与倍他乐克联用治疗舒张性心力衰竭的疗效观察[J].中国医药,2007,2(3):151-152. 被引量:6
  • 4无.慢性心力衰竭诊断治疗指南[J].中华心血管病杂志,2007,35(12):1076-1095. 被引量:3684
  • 5Wood P,Piran S,Liu PP.Diastolic heart failure:progress,treatment challenges,and prevention[J].Can J Cardiol,2011,27(3):302-310.
  • 6Owan TE,Hodge DO,Herges RM,et al.Trends in prevalence and outcome of heart failure with preserved ejection fraction[J].N Engl J Med,2006,355(3):251-259.
  • 7Jessup M,Abraham WT,Casey DE,et al.2009 focused update:ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults:a report of the American College of Cardiology Foundation/American Heart Association Task Force on PracticeGuidelines:developed in collaboration with the International Society for Heart and Lung Transplantation[J].Circulation,2009,119(14):1977-2016.
  • 8Cleland JG,Tendera M,Adamus J,et al.The perindopril in elderly people with chronic heart failure(PEP-CHF)study[J].Eur Heart J,2006,27(19):2338-2345.
  • 9Massie BM,Carson PE,McMurray JJ,et al.Irbesartan in patients with heart failure and preserved ejection fraction[J].N Engl J Med,2008,359(23):2456-2467.
  • 10McMurray JJ,Carson PE,Komajda M,et al.Heart failure with preserved ejection fraction:clinical characteristics of 4133 patients enrolled in the I-PRESERVE trial[J].Eur J Heart Fail,2008,10(2):149-156.

二级参考文献84

  • 1戴士鹏,李瑞霞,张建刚,耿涛,徐泽升.螺内酯对老年收缩性心力衰竭患者心室重构和安全性研究[J].实用老年医学,2013,27(8):666-669. 被引量:5
  • 2王方正,张澍,黄德嘉,华伟,孙宝贵,沈法荣,吴书林,王建安,方全,吴立群,王景峰,王冬梅,郭涛,陈新,中华医学会心电生理和起搏分会心脏再同步治疗专家工作组.心脏再同步治疗慢性心力衰竭的建议[J].中华心律失常学杂志,2006,10(2):90-102. 被引量:90
  • 3Colucci WS. Molecular and cellular mechanisms of myocardial failure. Am J Cardiol, 1997, 80(11A) : 15L-25L
  • 4Braunwald E,Bristow MR Congestive heart failure: fifty years of progress. Circulation, 2000, 102(20 Suppl 4) : Ⅳ14-23.
  • 5Hunt SA, Abraham WT, Chin MH, et al. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure) : developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation, 2005, 112 (12) :e154-235.
  • 6Swedberg K, Cleland J, Dargie H, et al. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary ( update 2005 ):The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. Eur Heart J, 2005, 26(11): 1115-1140.
  • 7Arnold JM, Liu P, Demers C, et al. Canadian Cardiovascular Society consensus conference recommendations on heart failure 2006 : diagnosis and management. Can J Cardiol, 2006, 22 (1): 23-45.
  • 8Heart Failure Society of America. HFSA 2006 Comprehensive Heart Failure Practice Guideline. J Card Fail, 2006, 12 ( 1 ) : e1-2.
  • 9Enright PL, Sherrill DL Reference equations for the six-minute walk in healthy adults. Am J Respir Crit Care Med, 1998, 158(5 pt 1) :1384-1387.
  • 10Troosters T, Gosselink R, Decramer M. Six minute walking distance in healthy elderly subjects. Eur Respir J, 1999, 14(2) : 270-274.

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