期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

纳米金颗粒在头颈肿瘤诊疗中的研究进展 被引量：1

原文传递
导出
摘要 纳米金颗粒具有独特的理化性能,在恶性肿瘤诊断和治疗中取得了许多重要进展.研究发现纳米金颗粒可以通过抑制血管生成、携带抗肿瘤药物以及光热效应等达到治疗肿瘤的目的;同时由于修饰后的纳米金对肿瘤细胞具有靶向性,在头颈肿瘤的早期诊断方面也具有重要的意义.本文就纳米金颗粒及其作为肿瘤探针、药物载体、光热效应摧毁肿瘤细胞、放疗增敏等方面的研究进行综述.
作者 卢晗 何晓光
机构地区 昆明医科大学 昆明医科大学第一附属医院耳鼻咽喉二科
出处 《国际耳鼻咽喉头颈外科杂志》 2014年第1期20-23,共4页 International Journal of Otolaryngology-Head and Neck Surgery
关键词 纳米技术(Nanotechnology) 头颈部肿瘤(Head and NECK Neoplasms) 纳米金颗粒(gold nanoparticles)
分类号 R739.91 [医药卫生—肿瘤]
  • 相关文献

参考文献24

  • 1Bozec A, Gros FX, Penault-Llorca F, et al. Vertical VEGF targeting: a combination of ligand blockade with receptor tyrosine kinase inhibition[J]. Eur J Cancer, 2008, 44 (13) : 1922- 1930.
  • 2Boisselier E, Astruc D. Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity[J]. ChemSocRev, 2009, 38 (6) : 1759-1782.
  • 3Lewinski N, Colvin V, Drezek R. Cytotoxicity of nanoparticles[J]. Small, 2008, 4 (1) : 26-49.
  • 4Parak W J, Gerion D, Pellegrino T, et al. Biological applications of colloidal nanocrystals[J]. Nanotechnology, 2003, 14 (7) : R15.
  • 5Raschke G, Kowarik S, Franzl T, et al. Biomolecular recognition based on single gold nanoparticle light scattering[J]. NanoLett, 2003, 3 (7) : 935-938.
  • 6Jain PK, E1-Sayed IH, El-Sayed MA. Au nanoparticles target cancer[J]. Nano Today, 2007, 2 (1) : 18-29.
  • 7Wang H, HuffTB, Zweifel DA, et al. In vitro and in vivo two- photon luminescence imaging of single gold nanorods[J]. Proc NatlAcadSciUSA, 2005, 102 (44) : 15752-15756.
  • 8Cobley CM, Chert J, Cho EC, et al. Gold nanostructures: a class of multifunctional materials for biomedical applications[J]. ChemSocRew, 2011, 40 (1) : 44-56.
  • 9Yang J, Eom K, Lim EK, et al. In situ detection of live cancer cells by using bioprobes based on Au nanoparticles[J]. Langmuir, 2008, 24 (21) : 12112-12115.
  • 10Mallidi S, Larson T, Tam J, et al. Multiwavelength photoacoustic imaging and plasmon resonance coupling of gold nanoparticles for selective detection of cancer[J]. Nano Lett,2009, 9 (8) : 2825-2831.

二级参考文献39

  • 1Chang MY, Shiau AL, Chen YH, et al.lncreased apoptotic potential and dose-enhancing effect of gold nanoparticles in combination with single-dose elinical electron beams on tumor-bearing mice[J]. doi:l 0.3969/j.issn.0253-9896.2011.11.041.Cancer Sci, 2008,99(7): 1479-1484.
  • 2Ding B, Deng Z, Yah H, et al. Gold nanoparticle self-similar chain strut'ture organized by DNA origami[J].J Am Chem Soc, 2010,132 (10):3248-3249.
  • 3Soisuwan S, Warisnoieharoen W, l,irdprapamongkol K, et al. Eeo-friendly synthesis of fucnidan-stabilized gold nannpartieles [J]. Am J Appl Sci, 2010,7(8):1038-1042.
  • 4Zhang X, Xing JZ, Chen J, et al.Enhanced radiation sensitivily in prostate cancer by gotd-nanoparticles[J].Clin Invest Med,2008,31 (3):E 160-E 167.
  • 5Roa W, Zhang X, Guo I,, et al. Gold nanoparticle sensitize radinuherapy of pt'ostate eaneer cells by regulation of the cell cycle[J]. Nanotechnology,2009,20(37):375101.
  • 6Kong T, Zeng J, Wang X. et al.Enhancement of radiation cytotoxicity in breast-cancer cells by localized attachment of gold nanoparticles[J]. Sma11,2008,4(9):1537-1543.
  • 7Hainfeld JF,Slatkin DN,Smilowitz HM.The use of gold nanoparticles to enhance radiotherapy in mice[J].Phys Med Biol,2004,49(18): 309-315.
  • 8Chang MY,Shiau AL,Chen YH,et al.lncreased apoptotic potentialand dose-enhancing effect of gold nanopartieles in combinatiml with single-dose clinical electron beams on tumor-bearing mice[J]. Cancer Science,2008,99(7): 1479-1484.
  • 9Brun E, Duchambon P, Blouquit Y,et al.Gold nanoparticles enhancethe X-ray-induced degradation of human centrin 2 protein[J]. Radiat Phys and Chem, 2009,78(3): 177-183.
  • 10Ferrari M.Cancer nanotechnology: opportunities and challenges[J]. Nat Rev Cancer,2005,5(3):161-171.

共引文献4

同被引文献13

引证文献1

国际耳鼻咽喉头颈外科杂志
2014年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部