曲马多联合芬太尼在骨科手术中的镇痛疗效分析

Analysis of the Analgesic Efficacy of Tramadol Combined with Fentanyl in Orthopedic Surgery

目的探究曲马多联合芬太尼在骨科术中镇痛疗效观察。方法资料选自在该院骨科行手术治疗患者64例,随机分成两组,每组32例,予以曲马多作对照组,予以曲马多联合芬太尼作研究组,分析两组不同时间内的镇痛效果和不良反应情况。结果研究组各时间点VAS镇痛效果均优于对照组,差异有统计学意义(P<0.05);且研究组多汗、恶心等不良反应的发生均少于对照组,差异有统计学意义(P<0.05)。结论骨科手术中予以曲马多与芬太尼联合麻醉镇痛,成效显著,有一定临床价值。

Objective To explore the analgesic efficacy of tramadol combined with fentanyl in orthopedic surgery. Methods The data of 64 patients underwent orthopedic surgical treatment from June, 2012 to June, 2013 in our hospital were selected, and the patients were randomly divided into two groups with 32 cases in each. The control group was given tramadol, and the study group was given tramadol combined with fentanyl. The analgesic effect and adverse reactions of two groups at different times were analyzed. Results The VAS analgesic effect of the study group at each time point was better than that of the control group, the differences were statistically significant（P〈0.05）; and the incidence of complications such as hidrosis, nausea and so on was less than that of the control group, the difference was statistically significant（P〈0.05）. Conclusion The analgesic effect of tramadol combined with fentanyl applied to orthopedic surgery is remarkable, and has certain clinical value.