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颅脑创伤性下丘脑垂体功能不全的临床诊断及治疗效果分析 被引量:2

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摘要 目的为了进一步观察和了解颅脑损伤后下丘脑垂体功能情况,分析和研究促肾上腺皮质激素(ACTH)、皮质醇(COR)、三碘甲状腺原氨酸(T3)、促甲状腺激素(TSH)的改变情况。方法 28例颅脑损伤患者作为观察组对象,28例健康患者作为对照组观察对象,通过应用酶联免疫法测定两组患者的垂体前叶激素、甲状腺功能和生殖激素的改变情况,根据患者的格拉斯哥昏迷评分(GCS评分)分析颅脑创伤严重程度与激素水平之间的关系。结果观察组患者血中三碘甲状腺原氨酸、促甲状腺素较对照组明显下降,而且重型颅脑损伤病情严重者其下降幅度越明显,两组间比较差异有统计学意义(P<0.05)。结论颅脑损伤患者通过监测其下丘脑垂体释放激素的改变情况可作为观察病情及评测预后的一项参考指标。
作者 卓少伟
出处 《中国实用医药》 2014年第21期48-49,共2页 China Practical Medicine
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