江西省2003年-2012年麻疹网络监测数据及质量控制分析

Analysis of network surveillance data and quality control of measles in Jiangxi province from 2003 to 2012

目的分析江西省麻疹网络监测数据和质量控制,评价实验室网络建立和运转情况。方法对江西省麻疹实验室网络正式建立以来10年的各项实验室监测指标进行统计学方法分析。结果对2003年-2012年检测麻疹IgM抗体8 033份标本,阳性率为40.81%;风疹IgM抗体3 787份标本,阳性率为17.80%;在204份咽拭子标本中分离到麻疹毒株19株,经鉴定为麻疹野病毒H1a基因型,风疹毒株13株,经鉴定为风疹野病毒1E基因型。麻疹疑似病例的标本实验室诊断率从2004年的16.60%上升到2012年的100%。国家麻疹实验室及WHO对省级麻疹实验室的职能考核、血清再证实与现场认证成绩为满分或优秀;省级麻疹实验室对市级麻疹实验室进行职能考核和血清标本再证实等各项质控指标逐年提高并达到较高水平。结论江西省已建立了麻疹/风疹血清学和病原学监测实验室网络,并且运转良好,在控制和消除麻疹工作的进程中发挥了积极作用。

Objective To analyze the network surveillance data and quality control of measles,and to evaluate the significance and running status of measles laboratory network in Jiangxi province.Methods Each surveillance indicator of the measles laboratory network in Jiangxi in recent 10 years were analyzed by statistics.Results From 2003 to 2012,measles IgM antibody was detected in 8 033 serum samples,the positive rate was 40.81%,while rubella IgM antibody was detected in 3 787 serum samples,the positive rate was 17.80%.Nineteen measles viral strains were isolated from 204 throat swab specimens,and 13 rubella virus strains were separated from the 204 specimens.The measles viral strains were proved to be H1a genotype and rubella virus strains were proved to be 1E genotype.The diagnosis rate of suspected measles specimens had improved from 16.60% in2004 to 100% in 2012.The proficiency test,serum reconfirmation and on-site evaluation of provincial-level laboratory were regarded as the best or excellent by national measles laboratory and WHO.The quality control indexes of the municipal-level measles laboratories has improved year by year and reached a higher level.Conclusion The serology and etiology laboratory surveillance network of measles and rubella has been established and operated well in Jiangxi,playing an important role in measles control and elimination.