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家兔TAS1R2基因与生长发育性状的关联性分析 被引量:1

Correlation Analysis Between TAS1R2 Gene and Growth Traits in Rabbit
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摘要 TASlR2基因是味觉受体I型家族的第2个成员。本试验采集新西兰兔共417个样本,采用PCR产物直接测序法检测了家兔TASlR2基因上的单核苷酸多态性(SNPs),分析不同基因型与日龄重的遗传效应。研究结果如下:家兔TASlR2基因exon6的c.1581G〉A突变基因型AA极显著影响40日龄、56日龄和84日龄家兔的体重以及35~84日龄的平均日增重(P〈0.01),可考虑将TASlR2基因作为家兔生产性状的候选基因,以期为家兔生长性状标记辅助选择提供理论依据。 TAS1R2 gene is the second member from taste receptor type I family. In this study, a total of 417 New Zealand rabbits were collected to analyze the single nucleotide polymorphism of rabbit TAS1R2 by direct sequencing method. The results as follows: genotype AA from the c.1581 G〉A mutation of rabbit TAS1R2 gene in exon 6 had significant effect on rabbit's 40-days weight, 56-days weight, 84-days weight and 35-84-days average daily gain (P〈0.01). So TAS1R2 gene was considered to candidate gene of rabbit's production traits, it might be to provide theoretical ba- sis for auxiliary selection for growth trait markers in rabbits.
出处 《四川畜牧兽医》 2015年第3期29-31,34,共4页 Sichuan Animal & Veterinary Sciences
关键词 TAS1R2基因 基因编码区单核苷酸多态性 生长性状 平均日增重 关联性分析 TASIR2 gene cSNPs Growth traits Average daily gain Correlation analysis
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  • 1Botstein D, et al. Construction of a genetic linkage map in man using restriction fragment length poly- morphisms[J]. American Journal of Human Genetics, 1980,32(3) :314.
  • 2Blumenfeld O O, Patnaik S K. Allelic genes of blood group antigens: a source of human mutations and cSNPs documented in the blood group antigen gene mutation database [J]. Human Mutation, 2004,23 (1) : 8-16.

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