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B细胞活化因子与炎症相关性疾病的研究进展 被引量：1

Research progress on the relationship of B cell activating factor and inflammation-related diseases
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摘要 B细胞活化因子(B cell activating factor,BAFF)作为肿瘤坏死因子超家族(tumor necrosis factor super family,TNFSF)配体的一员,是一种促炎细胞因子,通过结合3种不同受体调节炎症的发展过程。目前发现BAFF与感染、自身免疫、代谢紊乱、骨改建和肿瘤等炎症相关性疾病密切相关。本文就BAFF与炎症相关性疾病的研究进展作一综述。 B cell activating factor（BAFF）, as a member of tumor necrosis factor super family（TNFSF）, is one of proinflammatory cytokines through binding three different receptors to regulate the process of inflammation. Up to now, more and more researches have demonstrated that BAFF is associated with inflammation-related diseases such as infection, autoimmune diseases, metabolic disorders,bone remodeling and tumors. This review is to discuss the advancement of the relationship of BAFF and inflammation-related diseases.
作者 蒋少云
机构地区 天津医科大学口腔医学院口腔医院牙周科
出处 《武警后勤学院学报（医学版）》 CAS 2015年第1期71-76,共6页 Journal of Logistics University of PAP（Medical Sciences）
基金 国家自然科学基金(81100758/H1405)
关键词 B细胞活化因子 受体 信号通路 炎症 疾病 B cell activating factor Receptor Signaling pathway Inflammation Diseases
分类号 R593.22 [医药卫生—内科学]
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参考文献31

  • 1Fu LC, Lin-Lee YC, Pham LV, et M. BAFF-R promotes cell proliferation and survival through interaction with IKKβ and NF-KB/c-Rel in the nucleus of normal and neoplastic B- lymphoid cells [J]. Blood, 2009, 1 13(19):4627-4636.
  • 2Mecklenbrauker l, Kalled SL, Leitges M, et al. Regulation of B cell survival by BAFF-dependent PKCS-mediatcd nucle- ar signaling [J]. Natnre, 2004, 431 (7007):456-461.
  • 3Liu D, Li P, Song S, et al. Pro-apoptotic effect of epigallo- catechin-3-gallate on B lymphocytes through regulating BAFF/PI3K/Akt/mTOR signaling in rats with collagen-in- duced arthritis [J]. Eur J Pharmacol, 2012, 690(1-3):214- 225.
  • 4Kim MY, Kim DH, Do MS. B-cell-activating factor is a regu- lator of adipokines and a possible mediator between adipo- cytes and macrophagcs [J]. Exp Mol Med, 2013, 45:4.
  • 5Yang C, Li N, Wang Y, et al. Serum levels of B-cell activat- ing factor in chronic hepatitis B virus infection: association with clinical diseases [J]. J Interferon Cytokine Res, 2014, 34 (10):787-794.
  • 6McNamara PSI, Fonceca AM, Howarth D, et al. Respiratory syncytial virus infection of airway epithelial cells, in vivo and in vitro, supports pulmonary antibody responses by inducing expression of the B cell differentiation factor BAFF[J]. Tho- rax, 2013, 68(1):76-81.
  • 7Scholzen A, Teirlinck AC, Bijker EM, et al. BAFF and BAFF receptor levels correlate with B cell subset activation and re- distribution in controlled human malaria infection [J]. J Im- munol, 2014, 192(8):3719-3729.
  • 8Gumus P, Nizam N, Lappin DF, et al. Saliva and serum Lev- els of B-cell activating factors and tumor necrosis factor-al- pha in periodontitis patients [J]. J Periodontol, 2014, 85(2): 270-280.
  • 9Nile C J, Shetxabeh S, Ramage G, et al. Comparison of circu- lating tumour necrosis factor superfamily cytokines in peri- odontitis patients undergoing supportive therapy: a ease- controlled cross-sectional study comparing smokers and non-smokers in health and disease [J]. J Clin Periodontol, 2013, 40(9):875-882.
  • 10Gumus P, Buduneli E, Biyikoglu B, et al. Gingival crevicu- lar fluid and serum levels of APRIL, BAFF and TNF-alpha in rheumatoid arthritis and osteoporosis patients with peri- odontal disease [J]. Arch Oral Biol, 2013, 58(10):1302-1308.

同被引文献19

  • 1Platt MJ. Outcomes in preterm infants[J]. Public Health, 2014,128(5): 399-403.
  • 2Mwaniki MK, Atieno M, Lawn JE, et al. Long-term ueurodevelopmental outcomes after intrauterine and neonatal insults: a systematic review[J]. Lancet, 2012, 379(9814): 445-452.
  • 3Carroll S, Sebire N, Nicolaides K. Pre-term pre-labour amniorrhexis[J]. Curr Opin Obstet Gynecol, 1996, 8(6): 441-448.
  • 4Olson DM. The role of prostaglandins in the initiation of parturition[J]. In Best Pract Res Clin Obstet Gynaecol, 2003, 17(5): 717-730.
  • 5LeBlanc MM, Gigubre S, Lester GD, et al. Relationship between infection, inflammation and premature parturition in mares with experimentally induced placentitis [ J]. Equine Vet J Suppl, 2012, (41): 8-14.
  • 6Horliana AC, Chambrone L, Foz AM, et al. Dissemination of periodontal pathogens in the bloodstream after periodontal procedures: a systematic review[J]. PLoS One, 2014, 9(5): e98271.
  • 7Le6n R, Silva N, Ovalle A, et al. Detection of Porphyromonas gingivalis in the amniotic fluid in pregnant women with a diagnosis of threatened premature labor[J]. J Periodontol, 2007, 78(7): 1249-1255.
  • 8Katz J, Chegini N, Shiverick KT, et al. Localization of P. gingivalis in preterm delivery placenta[J].J Dent Res, 2009, 88(6): 575-578.
  • 9Ao M, Miyauchi M, lnubushi T, et al. Infection with Porphyromonas gingivalis exacerbates endothelial injury in obese mice[J]. PLoS One, 2014, 9(10): el 10519.
  • 10Ouhara K, Iwasaki Y, Kajiya M, et al. The differential expression of mgl mRNA by Porphyromonas gingivalis affects the production of methyl mercaptan[J]. Oral Dis, 2015, 21(5): 626-633.

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武警后勤学院学报（医学版）
2015年 第1期

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